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ID:33704537
大小:1.71 MB
页数:49页
时间:2019-02-28
《454例妊娠期肝内胆汁淤积症患者妊娠结局分析》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、分类号VDC硕士学位论文密级4S4侈lJ妊娠期肝内胆汁淤积症患者妊娠结局分析THEPREGNANCYOUTCOMEOF454CASESOFGESTATIONALCHOLESTASIS作者姓名:TanaKiak(他那)学科专业:临床医学学院(系、所):湘雅附二学院指导教师:张丽娟教师论文答辩日期叫苫二孑1}答辩委员会主席——姝中南大学二0一二年五月原创性声明lUlIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIY2422322本人声明,所呈交的学位论文是本人在导师指导下进行的研究工作及取得的研究成果。尽我所知,除了论文中特,另tlDi:l以标注和致谢的地方外,论文中不包
2、含其他人已经发表或撰写过的研究成果,也不包含为获得中南大学或其他单位的学位或证书而使用过的材料。与我共同工作的同志对本研究所作的贡献均已在论文中作了明确的说明。作者签名:t唧学位论文版权使用授权书本人了解中南大学有关保留、使用学位论文的规定,即:学校有权保留学位论文并根据国家或湖南省有关部门规定送交学位论文,允许学位论文被查阅和借阅;学校可以公布学位论文的全部或部分内容,可以采用复印、缩印或其它手段保存学位论文。同时授权中国科学技术信息研究所将本学位论文收录到《中国学位论文全文数据库》,并通过网络向社会公众提供信息服务。储躲幽L翮签劈群嗍世芦月血objective"Abstrac
3、tAssessingtheimpactofpotentialriskfactorsinAdversePerinatalOutcomeinIntrahepaticCholestasisofPregnancyMethod:DataofhospitaldeliveriesrecordswerecollectedfromJanuary2007toDecember201fromtheSecondXiangyaHospital.Clinicaldataof454casesofpatientswithICPand83casesinnormalpregnantwomenwhodeliveredd
4、uringthesameperiodWasrandomlyselectedandtherealtaionshipbetweentheclinicalandlaboratoryparametersandperinataloutcomewereanalysed.Results:1.Theincidencerateofpostpartumhemorrhage,cesareansection,lowbirthweightneonates,prematureneonates,fetaldistress,MSAFandfetaldeathwerehigherinICPgroupthaninC
5、ontrolGroup.TheincidenceratesofsevereICPgroupwerehigherthanthemildICPgroup,thedifferenceswerestatisticallysignificant(P6、thatofControlGroupwithresultsofTBA,ALT,AST,TBILandDBILwere6.914-2.67I_tmol/L,16.164-3.65U/L,20.18士6.01U/L,6.944-1.769mol/Land1.914-0.69mol/L)respectively,thedifferenceswerestatisticallysignificant(P<0.05).2.Therewerenosignificantdifferencesinlowbirthweightneonates,prematureneonates,fetaldistr7、essandMSAFinICPpatientswithadvancedmaternalage。Theincidencerateofneonatalasphyxiagraduallyincreasedwithincreasingmaternalage,thedifferenceWasstatisticallysignificant(P
6、thatofControlGroupwithresultsofTBA,ALT,AST,TBILandDBILwere6.914-2.67I_tmol/L,16.164-3.65U/L,20.18士6.01U/L,6.944-1.769mol/Land1.914-0.69mol/L)respectively,thedifferenceswerestatisticallysignificant(P<0.05).2.Therewerenosignificantdifferencesinlowbirthweightneonates,prematureneonates,fetaldistr
7、essandMSAFinICPpatientswithadvancedmaternalage。Theincidencerateofneonatalasphyxiagraduallyincreasedwithincreasingmaternalage,thedifferenceWasstatisticallysignificant(P
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