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1、提要目的:通过对痰瘀同治法治疗不稳定型心绞痛的临床研究，探讨冠心病不稳定型心绞痛新的治疗方法及疗效，探讨化痰祛瘀方治疗不稳定型心绞痛的机制，希望对中医药在治疗不稳定型心绞痛方面有所帮助。方法:将符合纳入标准的50例患者采取简单随机方法，分为治疗组25例和对照组25例。对照组采用西药常规治疗；治疗组在西药常规治疗的基础上加服具有化痰逐瘀，活血通脉功用的化痰祛瘀方，分别记录治疗前后心绞痛发作情况、中医症状的变化情况、血压、心电图、血液流变学、血脂四项、一氧化氮(NO)、纤维蛋白原，高敏C反应蛋白(hs–CRP)等指标。结果:临床观察表明，治疗组在改善患者临床症
2、状，调脂、降低血液粘度和血小板活化等方面均优于对照组(P<0.05)。结论:化痰祛瘀方是临床上治疗不稳定型心绞痛的一个服用安全、疗效确切的中药复方制剂，具有明显的临床治疗作用，其能抗动脉粥样硬化形成、稳定动脉粥样斑块，扩张冠状动脉、保护缺血心肌、改善心肌代谢，从而起到治疗心绞痛的作用。关键词痰瘀同治法；不稳定型心绞痛；胸痹心痛；化痰祛瘀方TheStudyofClinicalresearchonTreatingbothPhlegmandBloodstasisinTreatmentofUnstableAnginaPectorisSpeciality：Inter
3、nalMedicineofTraditionalChineseMedicineAuthor:GaoDezhenTutor:MengZhaoyangAbstractObjective:Bytreatingbothphlegmandbloodstasisinthetreatmentofunstableanginapectorisclinicalresearch,wehopetoexplorenewtreatmentsandtheefficacyofunstableangina,andexplorethemechanismofhuatanquyugranulei
4、nthetreatmentofunstableanginapectoris.AndwehopetohavethehelptotraditionalChinesemedicineinthetreatmentofunstableanginaaspects.Methods:Dividethe50patientswhowillmeettheinclusioncriteriaintothetreatmentgroup25casesandcontrolgroup25casesbysimplerandommethod.Thecontrolgroupuseconventi
5、onaltreatmentofWesternmedicine;ThetreatmentgroupaddstothemethodthathavethethefunctionofProfitingqi,dispelingphlegmandpromotingbloodcirculationononthebasisofthewesternmedicineconventiontreatmentfoundation.Beforeandafterthetreatmentrecordaroundseparatelytheanginapectorisoutbreaksitu
6、ation,theChinesemedicinesymptomchangesituation,thebloodpressure,theelectrocardiogram,thebloodrheology,fouritemsofbloodfats,thenitrogenmonoxide(NO),fibrinogen,GaoMinCtargets(hs-CRP)andotherindexes.Results:TheClinicalobservationshowsthatinimprovingtheclinicalsymptoms,regulatingblood
7、fats,reducingbloodviscosityandplateletactivationandotheraspects,thetreatmentgrouparebetterthanthecontrolgroup(P<0.05).Conclusion:HuatanquyugranuleisasafeandeffectiveChinesemedicinecompoundinthetreatmentofunstableanginapectoris,andhasobviousclinicaltherapeuticeffect.Itcansteadyathe
8、romatousplaque,dilatecoronaryarte
