伴童年创伤抑郁症的认知功能和认知模式分析

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1、ThecognitivefunctionandcognitivepatternsofdepressionAbstractwithchildhoodtraumaObjective：1)ToexplorertheimpactofchildhoodtraumaanddepressiononNeurocognitivefunction．2)Toinvestigatetherelationshipbetweenchildhoodtraumaandcognitivebiases．Methods：Patientsofmaiordepressionandth

2、ehealthyadultswereassessedbyChildhoodTraumaQuestionnaire(CTQ)．Thenthepatientsweredividedintothedepressiongroupwithchildhoodtraumaandwithoutchildhoodtrauma．aswellasthehealthyadultsweredividedintothecontrolgroupwithchildhoodtraumaandwithoutchildhoodtrauma．Allsubjectswereadmin

3、istratedforcognitivefunctionwithneuropsychologicaltests：theStroopcolorwordTest，TrailMakingTest，WisconsinCardSortingTest，Verbalfluencytest，andWechslerMemoryscaleeta1．AllsubjectsalsowereassessedforcogntivebiaseswithDysfunctionalAttitudesScales(DAS)andCognitiveBiasQuestionnair

4、e(CBQ)．Results：1、)ThemaineffectofdepressiondiagnosisexistedintheTrailMakingTest，theStroopcolorwordtest，WEST,Verbalfluencytest，andassociatedlearning，visualreproductionandunderstandingmemoryinWMS．2、lmaineffectsofchildhoodtraumawerefoundinthewordsoftheStroopcolorwordtestsubtes

5、ts，WEST,verbalfluencytestandvisualreproductiontestinWMS．3)IllnumberofpersistenterrorsinWCSTandverbalfluencytest，theinteractionofdepressionandchildhoodtraumawasfound，andthecontrolgroupwithoutchildhoodtraumahadasignificantdifferencewiththeotherthreegroups．4)Inthegroupswithchi

6、ldhoodtrauma，includingthedepressiongroupwithchildhoodtraumaandthecontrolgroupwithchildhoodtrauma)therewasnosignificantcorrelationbetweencognitiveimpairmentandthefiveformsofchildhoodtraumascore．5)Thecognitivebiasesquestionnairedepression-distortedscoreandVthefives缸ucnlrefact

7、orscoresofdysfunctionalattitude，whichincludingvulnerability,attractionandrepulsion，approval，dependencyandcognitivephilosophy,werehigherincontrolgroupwithchildhoodtraumacomparedtocontrolgroupwithoutchildhoodtrauma．(尸

8、depression—distort，weresignificantlyassociatedwithtotalscoreofCTQ．Multipleregressi