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1、提要目的：观察酒肝宁煎剂对酒精性肝损伤的临床疗效，探讨酒肝宁煎剂治疗酒精性肝损伤的作用机理。方法：将60例患者分为治疗组酒肝宁煎剂组和对照组各30例，分别在治疗2周和2月后观察两组的实验室指标、临床症状体征、影像学改变和外周血象以判断疗效，并对结果进行对比。结果：治疗2周后，治疗组总有效率86.67％，优于对照组66.67％（P<0.05），2月后二者无差异（P>0.05）,治疗组对临床症状体征的改善有明显优势。结论：酒肝宁煎剂抗肝损伤作用途径包括：保护肝细胞，减轻肝细胞炎症，减轻肝脏纤维化程度，从而使临床的中医证候
2、及实验室指标得以显著地改善。关键词酒肝宁煎剂；酒精性肝病；临床研究；作用机理ClinicalStudiesonTreatmentofAlcoholicLiverDiseasewithJiuganningDecoctionSpecialty：InternalMedicineofTCMAuthor：WangLipengTutor：Prof.YinXiaoxuanAbstractObjective:ToobservetheclinicalefficacyofJiuganningDecoctiononalcoholicliv
3、erinjuryandthemechanismoftreatingalcoholicliverinjury.Methods:60caseswithALDasthesample,weredividedintotwogroupsrandomly,thegroupofJiuganningDecoctionandthecontrolgroupwith30casesineachgroupandtoobserveimprovementoftheillness,includeLaboratorymarkers,Clinicalsy
4、mptoms,ImagingchangesandPeripheralhemogram.Results:after2weekstreatment,thetreatmentgrouptotaleffectiveratewas86.67%,higherthan66.67%incontrolgroup(P<0.05),after2monththereisnodifference(P>0.05),thetreatmentgroupofclinicalsymptomsandsignsofimprovementhaveobviou
5、sadvantages.Conclusion:theAntiliverinjuryinmiceofJiuganninginclude:protectinglivercell,alleviateliverinflammation,relieveliverfibrosis,thusmakingtheclinicalsyndromeoftraditionalChinesemedicineandlaboratoryindexescanbesignificantlyimproved.KeywordsJiuganningDeco
6、ction,Alcoholicliverdisease,ClinicalStudies,mechanismofaction目录引言...............................................................................................................................1临床研究................................................................
7、...............................................................2一、一般资料.......................................................................................................................2（一）病例来源................................................................
8、...................................................2（二）一般情况..................................................................................................................
