资源描述:
《酒肝宁煎剂治疗酒精性肝损伤的临床研究》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、提要目的:观察酒肝宁煎剂对酒精性肝损伤的临床疗效,探讨酒肝宁煎剂治疗酒精性肝损伤的作用机理。方法:将60例患者分为治疗组酒肝宁煎剂组和对照组各30例,分别在治疗2周和2月后观察两组的实验室指标、临床症状体征、影像学改变和外周血象以判断疗效,并对结果进行对比。结果:治疗2周后,治疗组总有效率86.67%,优于对照组66.67%(P<0.05),2月后二者无差异(P>0.05),治疗组对临床症状体征的改善有明显优势。结论:酒肝宁煎剂抗肝损伤作用途径包括:保护肝细胞,减轻肝细胞炎症,减轻肝脏纤维化程度,从而使临床的中医证候
2、及实验室指标得以显著地改善。关键词酒肝宁煎剂;酒精性肝病;临床研究;作用机理ClinicalStudiesonTreatmentofAlcoholicLiverDiseasewithJiuganningDecoctionSpecialty:InternalMedicineofTCMAuthor:WangLipengTutor:Prof.YinXiaoxuanAbstractObjective:ToobservetheclinicalefficacyofJiuganningDecoctiononalcoholicliv
3、erinjuryandthemechanismoftreatingalcoholicliverinjury.Methods:60caseswithALDasthesample,weredividedintotwogroupsrandomly,thegroupofJiuganningDecoctionandthecontrolgroupwith30casesineachgroupandtoobserveimprovementoftheillness,includeLaboratorymarkers,Clinicalsy
4、mptoms,ImagingchangesandPeripheralhemogram.Results:after2weekstreatment,thetreatmentgrouptotaleffectiveratewas86.67%,higherthan66.67%incontrolgroup(P<0.05),after2monththereisnodifference(P>0.05),thetreatmentgroupofclinicalsymptomsandsignsofimprovementhaveobviou
5、sadvantages.Conclusion:theAntiliverinjuryinmiceofJiuganninginclude:protectinglivercell,alleviateliverinflammation,relieveliverfibrosis,thusmakingtheclinicalsyndromeoftraditionalChinesemedicineandlaboratoryindexescanbesignificantlyimproved.KeywordsJiuganningDeco
6、ction,Alcoholicliverdisease,ClinicalStudies,mechanismofaction目录引言...............................................................................................................................1临床研究................................................................
7、...............................................................2一、一般资料.......................................................................................................................2(一)病例来源................................................................
8、...................................................2(二)一般情况..................................................................................................................