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ID:32909900
大小:1.83 MB
页数:37页
时间:2019-02-17
《老年卒中相关性肺炎发生多重耐药菌感染的危险因素及病原学分析》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、重庆医科大学硕士学位论文老年卒中相关性肺炎发生多重耐药菌感染的危险因素及病原学分析姓名:纪风兵申请学位级别:硕士专业:内科学指导教师:卓超201204重庆医科大学硕士研究生学位论文老年卒中相关性肺炎发生多重耐药菌感染的危险因素及病原学分析摘要目的探讨老年卒中相关性肺炎(SAP)患者发生多重耐药菌感染的危险因素、多重耐药菌的分布及耐药情况。方法回顾性分析我院神经内科2007年6月至2011年6月的老年SAP患者的临床资料,1)危险因素分析:通过x2检验分别比较各个因素组SAP发生多重耐药菌感染的发病率的差异,经单因素分析后选取P<0.05的因素进行多因素
2、回归分析,2)病原学调查:多重耐药菌的病原菌分布、常见多重耐药菌菌株的耐药情况。结果单因素分析显示,卒中类型、SAP类型、意识水平、入住病房、接受胃管、预防性应用抗生素等因素存在统计学差异(P3、发性肺炎、入住ICU病房是SAP发生多重耐药菌感染的危险因素;多重耐药菌所占比例较高,对多种抗生素呈广重庆医科大学硕士研究生学位论文泛的不同程度的耐药。关键词:卒中相关性肺炎;多重耐药菌感染;危险因素:病原学重庆医科大学硕士研究生学位论文RISKFACToRSANDETIOLoGYoFSTROKEASSOCIATEDPNEUMoNIAINELDERLYPATIENTSWITHMUIJIPLEDRUG—RESISTANTBACTERlALINFECTIoNSABSTRACTObjectiveTodiscusstheriskfactors,thedistr4、ibutionanddrugresistanceofmultipledrug—resistantbacteriaofstrokeassociatedpneumonia(SAP)inelderlypatientswithmultipledrug。resistantbacterialinfections.MethodsAretrospectivestudywasdesignedtoanalyzetheclinicaldataofelderlypatientswithSAPfromJune2007toJune2011,1)RiskFactors:Compar5、isoninincidenceofSAPpatientswithmultipledrug.resistantinfectionbetweendifferentgroupsbychisquaretest.Multivariableregressionanalysiswasusedafterunivariateanalysis.2)Etiologicalinvestigation:distribmionofmultipledrug—resistantbacteria,dnlgresistanceofcommonmultipledrug-resistantb6、acteria.ResultsUnivariateanalysisindicatedthattherewasstatisticaldifferencebetweenthetwogroupsdividedbytypeofstrokelevelofconsciousnessSAPtypewardtypereceivingstomachTubeandprophylacticantibiotics.Multivariableregressionanalysisindicatedthat4重庆医科大学硕士研究生学位论文therewasstatisticalsig7、nificantindistm'banceofconsciousnessLate.OnsetPneumoniaandICUward.Thereare182strainsin154patients,including15multipledrug—resistantstrains(Pvaluewere0.001,0.001,0.038).Among38multipledmg-resistantstrainsthefirst5strainswereAcinetobacterbaumannii,Pseudolnonasaemginosa,Klebsiellap8、neumoniae,Hemolyticstaphylococcus,Staphylococcu
3、发性肺炎、入住ICU病房是SAP发生多重耐药菌感染的危险因素;多重耐药菌所占比例较高,对多种抗生素呈广重庆医科大学硕士研究生学位论文泛的不同程度的耐药。关键词:卒中相关性肺炎;多重耐药菌感染;危险因素:病原学重庆医科大学硕士研究生学位论文RISKFACToRSANDETIOLoGYoFSTROKEASSOCIATEDPNEUMoNIAINELDERLYPATIENTSWITHMUIJIPLEDRUG—RESISTANTBACTERlALINFECTIoNSABSTRACTObjectiveTodiscusstheriskfactors,thedistr
4、ibutionanddrugresistanceofmultipledrug—resistantbacteriaofstrokeassociatedpneumonia(SAP)inelderlypatientswithmultipledrug。resistantbacterialinfections.MethodsAretrospectivestudywasdesignedtoanalyzetheclinicaldataofelderlypatientswithSAPfromJune2007toJune2011,1)RiskFactors:Compar
5、isoninincidenceofSAPpatientswithmultipledrug.resistantinfectionbetweendifferentgroupsbychisquaretest.Multivariableregressionanalysiswasusedafterunivariateanalysis.2)Etiologicalinvestigation:distribmionofmultipledrug—resistantbacteria,dnlgresistanceofcommonmultipledrug-resistantb
6、acteria.ResultsUnivariateanalysisindicatedthattherewasstatisticaldifferencebetweenthetwogroupsdividedbytypeofstrokelevelofconsciousnessSAPtypewardtypereceivingstomachTubeandprophylacticantibiotics.Multivariableregressionanalysisindicatedthat4重庆医科大学硕士研究生学位论文therewasstatisticalsig
7、nificantindistm'banceofconsciousnessLate.OnsetPneumoniaandICUward.Thereare182strainsin154patients,including15multipledrug—resistantstrains(Pvaluewere0.001,0.001,0.038).Among38multipledmg-resistantstrainsthefirst5strainswereAcinetobacterbaumannii,Pseudolnonasaemginosa,Klebsiellap
8、neumoniae,Hemolyticstaphylococcus,Staphylococcu
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