牵正复颜饮治疗风痰瘀阻型周围性面瘫的临床研究

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1、提要目的：本研究通过观察120例风痰瘀阻型周围性面瘫患者治疗前后的症状、体征及疗效性指标的变化情况，比较治疗组和对照组治疗前后及组间的症状、体征及疗效差异，观察牵正复颜饮对风痰瘀阻型周围性面瘫的治疗作用。方法：统计2010.1～2011.12门诊风痰瘀阻型周围性面瘫患者120例，按就诊顺序随机分为治疗组牵正复颜饮组和对照组大活络胶囊组，每组各60例，2周为一个治疗疗程，两组均治疗2个疗程，随访1个月，观察治疗前、治疗2周、4周及随访时，两组患者House-Brackmann量表评分、中医症状积分的改善程度；并观察治疗前和治疗4周后两组患者面部

2、残疾指数（FDI）（包括躯体功能FDIP评分和社会生活功能FDIS评分）的改善情况。结果：经统计学分析，治疗后各时点两组患者在House-Brackmann量表临床疗效、分级、积分，中医症状临床疗效、积分等指标的改善方面，治疗组优于对照组（P＜0.05）；治疗前后PDIS和PDIP评分两组均有非常显著性差异（P＜0.01），治疗组明显优于对照组（P＜0.01）。结论：牵正复颜饮治疗风痰瘀阻型周围性面瘫临床疗效显著，既能明显改善患者的面部症状和体征，又能提高患者生活质量、心理水平，是治疗周围性面瘫安全有效的方药。关键词周围性面瘫；牵正复颜饮；临

3、床研究；疗效TheClinicalResearchonQianZhengFuYanYiinTreatingFacialPalsyofWindPhlegmObstructionSpeciality：ClinicalbasicresearchofTraditionalChineseMedicineAuthor：ZhaoJinTutor：Prof.CaoXiaolanAbstractObjective:Thisstudycomparedthechangesofsymptoms,signsandefficacyindicatorsbeforeanda

4、ftertreatmentin120casesofwindphlegmobstructionfacialpalsypatients,toobservedqianzhengfuyanyinintreatingFacialpalsyofwindphlegmobstruction.Methods:120outpatientsofwindphlegmobstructionfacialpalsy,duringJanuary2010toDecember2011,weredividedintotreatmentgroupandcontrolgroupacc

5、ordingtothedoctororderrandomlyandequally.Treatmentgroupusedqianzhengfuyanyin,whilecontrolgroupusedDaHuoluocapsule.Twoweekswereacourse.Aftertwocoursestherewasafollow-up-visitmonth.House-BrackmannscalescoreandTCMsymptomscoreimprovementwereobservedbeforetreatment,aftertwoweeks

6、,fourweeksandafollow-up-visitmonth.FacialDisabilityIndex(FDI)improvement,includingFDIPscoreforbodyfunctionandFDISscoreforsociallifefunction,wasobservedbeforetreatmentandafterfourweeks.Result:Clinicalefficacy,grading,andintegrationofHouse-Brackmannscalescoreandclinicaleffica

7、cy,integrationofTCMsymptomscoreinthetreatmentgroupwerebetterthanthatinthecontrolgroup(P<0.05).FDIPscoreandFDISscoreaftertreatmentweremuchbetterthanbeforetreatmentinbothtwogroups(P<0.01),butindexesinthetreatmentgroupwerebetterthanthatinthecontrolgroup(P<0.05).Conclusion:Ther

8、eissignificantclinicaleffectinimprovementinthefacialsignsandsymptoms,qualityoflife