参芪地黄汤化裁对治疗慢性肾功能衰竭早中期气阴两虚证的临床研究

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1、提要目的：为探索治疗慢性肾功能衰竭早中期的有效方法，根据其脾肾气阴两虚、瘀浊内阻的病机特点，提出益气养阴、活血除湿为根本治法，并拟定参芪地黄汤化裁，从临床观察进行了研究。方法：临床将60例早中期慢性肾衰患者随机分为参芪地黄汤化裁治疗组，和开同对照组。给药8周后，检测患者相关实验室检查，并观察患者的证候改变。结果：临床研究表明，本方能有效改善临床症状和体征，能明显降低患者尿蛋白定量及定性指数、尿红细胞计数、Scr、血β2-MG，提高肾功能，总有效率83.33％，显著优于对照组。结论：本方对改善微循

2、环、恢复肾功能有良好作用，是治疗慢性肾衰的有效方剂。关键词慢性肾功能衰竭；气阴两虚瘀浊内阻；中医治疗；益气养阴TheClinicalresearchofShenqiDihuangDecoctiontotreatSyndromeofdeficiencyofQiandYininearlyandmiddlestageofCRFSpecialty:SurgeryofTCMAuthor:CongXiaoxiaoTutor:Pro.SiGuominAbstractObjective:Toexplorthee

3、ffectivetreatmentofearlyandmetaphaseinCRF,accordingthepathogenesischaracteristicsofspleenandkidneydeficiencyofbothqiandYin,putforwardthetreatmentofsupplementingqiandnourishingyin,promotingbloodcirculationanddehumidification,protocoltheprescriptionofS

4、henqidihuangTang.Researchthroughthecinicalobservation.Methods:60patientswithCRFinearlyandmetaphasewererandomlydividedintotreatmentgroupandcontrolgroupwith30patientseach.ThepatientsintreatmentgroupweregavenShenqidihuangTang.Thepatientsincontrolgroupwe

5、regavenCompoundα-KetoacidTablets.After8weeks,testthelaboratorydataofallpatientsandobservethechangeofsyndrome.Results:TheprescriptioncaneffectivelyimprovesymptomandsignsofCRFpatients,obviouslyreducetheurinaryprotein,urinaryredcell,SCR,bloodβ2-MG.andim

6、proverenalfunction.Thetotalefficiencywas83.33%andobviouslybetterthancontrolgroup.Conclusion:ShenqidihuangTangshowagoodroletoimprovemicrocirculation,recoveryrenalfunction.It’saeffectiveprescriptiontotreatCRF..Keywords:CRF;deficiencyofbothqiandYin;Trad

7、itionalChinesemedicinetreatment;supplementingqiandnourishingyin目录引言...............................................................................................................................1临床研究...................................................

8、............................................................................2一、临床资料.......................................................................................................................2（一）一般资料........................................