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1、P134ParagonimuswestermaniParagonimuswesternaniwasfirstdescribedfromtwoBengaltigerthathaddiedinzoosinEuropein1878.Duringthenext2years,infectionsbythisworminhumanswerefoundinFurmosa.Itwasveryquicklyfoundinthelungs,brain,andvisceraofhumansinJapan,Korea,andthePhilipp
2、ines.ThelifecyclewasworkedoutbyKobayashiandYokagawa.ThemajorfocusofinfectiontodayremainsintheOrient,includingIndiaandthePhilippines.ItalsoappearstobeendemicthroughouttheEastIndies,NewGuinea,theSolomonIslands,Samoa,westernAfrica,Peru,Colombia,andVenezuela.Thetaxon
3、omyofthegenusisdifficult,andsomeofthesereportsmaybeofother,closelyrelatedspecies.Paragonimiasisisanexcellentexampleofzoonosis.并殖吸虫卫氏并殖吸虫人兽共患型Paragonimuswestermani斯氏狸殖吸虫兽主人次型Pagumogonimusskrjabini卫氏并殖吸虫（肺吸虫）Paragonimuswestermani一、形态口吸盘卵肠支成黄腹吸盘腺卵巢虫子子宫宫睾丸睾丸卵黄腺虫卵大小中等
4、大小卵盖形状不规则椭圆形卵细胞颜色金黄色卵壳卵壳厚薄不一卵黄细胞1个卵细胞、内容物10多个卵黄细胞其他卵盖大、常倾斜、卵壳也可缺如二、生活史（野猪、野鼠）滞育童虫（痰、粪便）入水卵毛蚴胞蚴母雷蚴子雷蚴尾蚴囊蚴成虫溪蟹（肺）川卷螺人、犬、猫、虎等体内移行穿肠壁腹腔穿膈肌胸腔肺窜扰肝、脑、皮下Lifecycle1、感染期：囊蚴2、感染方式：生吃含囊蚴的溪蟹、转续宿主的肉（猪肉）3、寄生部位：肺、异位寄生4、终宿主：人5、保虫宿主：犬、猫、虎三、致病（pathogenesis)急慢脓肿期性性期期囊肿期纤维疤痕期三、致病（pat
5、hogenesis)Theearly,invasionstagesofparagonimiasiscausefewornosymptomaticpathologicalconditions.Onceinalungoranectopicsite,thewormstimulatesconnectivetissueproliferationthateventuallywillenshrouditinabrownishorbluishcapsule.Suchcapsulesoftenulcerateandhealslowly.E
6、ggsinsurroundingtissueswillthemselvesbecomecentersofpseudotubercles.Wormsinthespinalcordareknowntocauseparalysis,whichsometimesisfatal.FatalcasesofParagonimusinthehearthavebeenrecorded.Cerebralcaseshavethesameresultsasthoseofcerebralcysticercosis.Pulmonarycasesus
7、uallycausechestsymptoms,withbreathingdifficulties,chroniccough,andsputumcontainingbloodorbrownishstreaks.Fatalcasesarecommon.胸肺型腹型临皮下包块型床分脑脊髓型型亚临床型其他型录像四、诊断（diagnosis)病痰检虫卵原学粪检虫卵诊活组织检查断免疫学诊断五、流行与防治(EndemityandPrevention)（野猪、野鼠）滞育童虫（痰、粪便）3入水卵毛蚴胞蚴母雷蚴子雷蚴尾蚴囊蚴成虫1溪蟹（肺）
8、川卷螺2人、犬、猫、虎等传染源流行患者××，男，22岁，云南盐津人，小学教师。主诉反复咳嗽，胸痛，胸闷伴气紧一年多，于95年11月入院。患者于95年六月不明原因出现畏寒，双侧胸痛，咳嗽，食欲减退。于当地县医院就医，摄胸片发现侧胸腔积液，诊断为结核性胸膜炎。经抗炎，抗结核治疗近五月后，上述症状明显好转。但同年10月又出
