肝癌肝移植术后复发和转移特点及预后因素

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1、ᇏݓൌႨຓ॓ᄖᆽ୍ᄅज௹·655·ંᇷ໓ᅣщğčĎٳ෍ၹުყࠣห၍ሇބگުඌᆱ၍ۉδۉ༅৙ဎࢭđઔၪđݒᆽႧđᇫཫڂđޅཫඨ}ᅋေ~ଢฐษۉ༥Іδۉ၍ᆱඌުᇖਿگބሇ၍หđٳ༅႕ཙఃყުາགၹ෍bٚم߭ܤྟݔࢲ٠ෛބਘሧԵਢದѨᆱ၍ۉྛδІ༥ۉ২ჽ၂၄උڸ࿐ն೶ᇏᄅ୍ᇀᄅ୍༅ٳbႋႨ,BQMBONFJFSٳ෍ၹֆቓѓᆷ৘ѨԵਢཛ۲ؓဒ࡟LOB3PH-Ⴈ০đੱࠃթࠒ৆ުඌ࠹๤م༅đ০Ⴈ$PYб২ٳOPTOPNE&a௜ඣ1'"భ

2、ඌaٳaඔ۱aཬնਿᇖğൕཁ༅ٳ෍ၹֆݔࢲb༅ٳ෍ၹ؟ྛࣉ྘ଆ݂߭གڄࠩa૊࣡ઝ౓ٳOPTOPNE&aཬնਿᇖğൕཁ༅ٳ෍ၹ؟྘ଆ݂߭གڄYP$ĠܱႵުყა௹ٳ./5Qaٕࠩa૊࣡ઝ౓၂۱ᆱ၍ۉ൞ಖಯδІ༥ۉંࢲb෍ၹགາ৫׿ުყದѨཙ႕൞ٕᇶေൡႋᆣbඌభᇖਿնཬa&ENPOTPO۬࿸Ġ෍ၹေᇶቋުყದѨᆱ၍ۉδۉཙ႕൞ٕ౓ઝ࣡૊aࠩٳೱ࿊൳ุđॖ൐ѨದࠆӉ௹թࠃb}ܱ࡯Ս~ۉ༥ІδĠۉ၍ᆱĠᇖਿگĠყުᇏ๭োٳğ3໓ངѓᆽ઒ğ"Recurrenceandmetastasisprofilesofhepatocel

3、lularcarcinomaafterlivertransplantationandanalysisofprognosticfactorsLIYan-jieđMAYiđGUOZhi-yongđetal.OrganTransplantationCenter,theFirstAffiliatedHospitalofSunYat-senUniversity,Guangzhou510080,ChinaCorrespondingauthorğMAYiđE-mailğanhuimayi2002@163.comAbstractOb

4、jectiveToexplorethefeaturesofrecurrenceandmetastasisofhepatocellularcarcinoma(HCC)afterlivertransplantation,andanalyzetheriskfactorsinfluencingprognosis.MethodsTheclinicalandfollow-updataof121patientswhounderwentlivertransplantationforHCCbetweenJune2007andOctob

5、er2010intheFirstAffiliatedHospitalofSunYat-senUniversitywereanalyzedretrospectively.TheKaplan-meiermethodwasusedtoevaluatethecumulativesurvivalrate.Log-ranktestandCoxregressionmodelwereperformedtoanalyzeclinicalpathologicriskfactorsbyunivariateandmultivariatean

6、alysisrespectively.ResultsIntheunivariateanalysis,tumorsize,numberandlocation,preoperativealpha-fetalprotein(AFP)level,Edmondsonpatho1ogicclassification,portalveininvasionandpTNMstagewerefoundtobeassociatedwiththeoverallsurvivalratesignificantly.Themultivariate

7、analysisrevealedthattumorsize,Edmondsonpatho1ogicclassificationandportalveininvasionwerethemostindependent,statisticalandsignificantfactorsaffectingsurvival.ConclusionHCCisstilloneofthemainindicationsoflivertransplantation.Tumorsize,Edmondsonpatho1ogicclassific

8、ationandportalveininvasionarethemajorprognosticfactorsafterlivertransplantation.Recipientscangetalong-termsurvivaliftransplantcandidatesareselectedstrictly.Keywordshepatocel