异丙酚对无痛人工流产术病人呼吸力学的影响

《异丙酚对无痛人工流产术病人呼吸力学的影响》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。

1、维普资讯http://www.cqvip.com中华麻醉学杂志2004年lO月第24卷第lO期ChinJAnesthesiol，October2004，Vol24，No．10745·临床研究·异丙酚对无痛人工流产术病人呼吸力学的影响石嵩张炳熙【摘要】目的观察异丙酚对人工流产病人呼吸气体流速的影响，以期将异丙酚对呼吸的抑制程度进行量化描述。方法择期行无痛人流术的早期妊娠病人4JD例，ASAI级，异丙酚静脉麻醉。首次剂量为2．5mg／kg，根据术中情况静脉追加3O～50mg。监测脉率及脉搏血氧饱和度。热线风速仪参数设定为：

2、采样频率100Hz，时间81．96S。在麻醉前、后分别采样。观察每例病人麻醉前、后脉率、血氧饱和度、呼吸暂停发生率、及吸气、呼气相平均及气流最大速度、气体流量及动压、呼吸频率及平均每次吸气、呼气时间等呼吸力学相关指标。结果与麻醉前比较，异丙酚麻醉后血氧饱和度下降(P<0．O1)，吸气、呼气相平均及气流最大速度、气体流量及动压下降(P<0．05)，其中吸气相的改变尤其明显(P<0．O1)，呼吸频率增加(P<0．O1)，平均每次吸气、呼气时间缩短(P<0．O1)。结论异丙酚静脉麻醉后病人呼吸气流速度、流量及气体动压均降低，

3、尤以吸气相更为明显。【关键词】呼吸力学；二异丙酚；流产，人工TheinfluenceofpropofolonrespiratorymechanicsduringpainlessinducedabortionSH／Song，ZHANGBing-xi．DepartmentofAnesthesiology，BeijingTongrenHospital，CapitalUnivesofMedicalScience，Beijing100730．c^ina【Abstract】ObjectivePropofolhaspro~undin

4、fluenceonrespiration．Thepurposeofthisstudywastoevaluatetheefectofpropofolonrespiratorymechanicsduringpainlessinducedabortion．MethodsFortyASA1womeninearlypregnancy(45—60days)aged17—52yrs，weighing42—80kgundergoinginducedabortionwereenroUedinthisstudy．Anesthesiawas

5、inducedwithintravenous2．5mg‘kg～andmaintainedwithintermittenti．v．bolusesofpropofol30—50mg．SpO2andHRweremonitoredwithNeHcorN一180pulseoximeter．RespiratorymechanicsWaSmonitoredwithIFA一300anemometer(TSICo．USA)．Theparametemmeasuredincludedinspiratory／expiratorymaximal

6、air-flowvelocity，inspiratory／expiratorymeanairflowvelocity，meaninspiratoryandexpiratorytime，respiratoryrate，inspiratory／expiratoryairflowvolume，dynamicinspiratoryandexpiraoryairwaypressureandindidenceofapnea．ResultsSpO2decreasedsignificantlyduringmaintenanceofan

7、esthesiawithpropofo1．Themeanandmaximalinspiratory／expiratoryairflowvelocityandtheinspiratory／expiratoryairflowvolumealldecreasedsignificantlyduringpropofolanesthesia．Thedynamicinspiratory／expiratoryairwaypressuresignificantlydecreasedduringpropofolanesthesia．The

8、respiratoryrateWassignificantlyhigherduringpropofolanesthesiawhilethemeaninspiratory／expiratorytimebecamesho~er．Threepatientsdevelopedapneaduringinductionofanesthesia