72例绝经后宫颈上皮内瘤变的临床与病理分析

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1、万方数据重庆医科大学硕士研究生学位论文英文缩写CINECCTCT英汉缩略语名词对照英文全称CervicalintraepithelialneoplasiaEndocervicalcurettageLiquid—basedthinlayercytologytest中文全称宫颈上皮内瘤变宫颈管刮术液基细胞学检查LEEPLoopelectrosurgicalexcision宫颈环形电切术procedure万方数据重庆医科大学硕士研究生学位论文72例绝经后宫颈上皮内瘤变的l临床及病理分析摘要目的：探讨绝经后宫颈上皮内瘤变(cervicalintraepithelialneopla

2、sia，CIN)的临床诊断及治疗。方法：回顾性分析2008年3月．2013年3月重庆医科大学附属第一医院收治的绝经后CIN高度病变(CINII、CINIII及累腺)的患者72例，术前采用阴道镜活检联合宫颈管刮术明确诊断，行全子宫切除术，并对其术后病理结果进行分析。结果：72例患者中有43例无临床症状，29例表现为不规则阴道流血和接触性出血。72例患者均经病理证实，其中9例患者为阴道镜活检阴性而宫颈管刮术(endocervicalcurettage，zcc)提示CINIII。8例患者术前诊断为CINII或CINIII，术后病检提示镜下早期浸润癌。结论：小于65岁的绝经后女性

3、应常规行宫颈细胞学筛查，宫颈细胞学异常者应取活检并行宫颈管刮术。绝经后CIN高度病变者的治疗方式可选择全子宫切除术。关键词：绝经后宫颈上皮内瘤变宫颈管刮术全子宫切除术万方数据重庆医科大学硕士研究生学位论文ClINICALANFPATHOLOGICALSTUDYOFCERVICALINTRAEPITHELIALNEoPLASIAINPoSTMENOPAUSALWOMENIN72CASESABSTRACTObjective：Toevaluatetheclinicalsignificanceofdiagnosisandtreatmentofcervicalintraepithe

4、lialneoplasia(CIN)inpostmenopausalWOmen．Methods：SeventytwopostmenopausalwomenwithhighgradeCINtreatedinTheFirstAffiliatedHospitalofChongQingMedicalUniversitybetweenMarch2008andMarch2013wereretrospectivelyidentified．Preoperativediagnosiswasestablishedusingcolposcopicbiopsyandendocervicalcur

5、ettage．TotalhysterectomywasperformedandthepreoperativediagnosticresultswerecomparedwithpostoperativepathologicaldiagnosisResults：43patientswereasymptomatic，29patientshadintermittentirregularvaginalbleedingandtonchbleeding．EndocervicalcurettagerevealedCINIIIin9patientswhiletheircolposcopic

6、biopsyresultswerenegative．8patientswerediagnosedpreoperativelyasCINIIandCINIIIandtheirpostoperativepathologicaldiagnosisturnedoutearlyinvasiveCanCer．j万方数据重庆医科大学硕士研究生学位论文Conclusion：Cervicalcytologytestshouldbeperformedroutinelyinpostmenopausalwomenunderageof65years．Inthosewhosecervicalcyto

7、logytestswereabnormal，furthercolposcopicbiopsyandendocervicalcurettageshouldbeperformed．ForthosepatientswithhighgradeCIN，totalhysterectomyisasuitabletreatmentoptionKeyWords：postmenopausalwomen，cervicalintraepithelialneoplasia，endocervicalcurettage，totalhysterectomy万