22例卵巢透明细胞癌合并卵巢子宫内膜异位症临床病理分析

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1、(2)Themainlysymptomsofpatientsinthreegroupswerepelvicmass，abdominaldistention，irregularvaginalbleeding，dysmenorrheaandfrequenturination，butthereWasnosignificantdifferenceamongthreegroups(尸>O．05)．(3)ThereWasnomixedepithelialcarcinomaingroupA，onecase(6．7脚ingroupB，

2、7cases(18．4％)ingroupC．Buttherewasnosignificantdifferenceamongthreegroups(尸>0．05)。(4)Throughultrasoundexamination，GroupCshowedmorecysticandsolidmixedmassthanothergroups(X2=6．866，卢O．032)，butthedifferencebetweengroupAandgroupBhadnostatisticalsignificance(胗0．05)，the

3、differenceWasnotstatisticallysignificantbetweengroupAandgroupC(尸>O．05)，thedifferencebetweengroupBandgroupChadstatisticalsignificance(Z2=4．414，芦0．036)．ThetumorsizeandCAl25levelshadnostatisticalsignificanceamongthreegroups(尸>0．05)．(5)MostofthepatientsingroupsAandB

4、werediagnosedatstageI，andsignificantlyhigherthanthatingroupC(X2=6．101，卢O．047)，andthedifferencebetweengroupAandgroupBhadnostatisticalsignificance(胗O．05)，thedifferencewasstatisticallysignificantbetweengroupsignificanceWasobtainedbetweengroupAandgroupC(尸：O．040)，nos

5、tatisticalBandgroupC(胗O．05)．ThereWasnostatisticalsignificanceamongthepatientswhichwerediagnosedatstageII，1IIandIV(尸>O．05)．3Thefive．yearsurvivalrateofthethreegroupswere50．O％，71．4％，36．8％，respectively，nosignificantdifferenceWasobserved(胗O．05)．Conclusions：Mostoftheo

6、varianendometriosis．associatedovariancleareellcarcinomapatientswerefoundtobeyounger，nonporous，andatanearlystage，havingshowedmorecysticmassandlowerCA125、析tllbetterprognosis．Youngpatientswitllovarianendometriosisstillneedtowaryofthemalignanttransformation．Keywords

7、：EndometriosisOvarianclearcellcarcinomaMalignanttransformation422例卵巢透明细胞癌合并卵巢子宫内膜异位症临床病理分析硕士研究生：朱丽莎指导教师：邓燕杰教授指导小组：姜继勇教授于晓辉教授专业名称：妇产科学刖吾卵巢肿瘤是女性生殖器的常见肿瘤之一，而卵巢癌是妇科恶性肿瘤中死亡率最高的肿瘤。其中起源于苗勒氏管的卵巢透明细胞癌(ovarianelearcellcarcinoma，OCCC)发病率占卵巢癌的5-25％，占卵巢恶性上皮性肿瘤的60．90％。而直到1973

8、年，世界卫生组织(WHO)由于OCCC独特的组织学和生物学表现才将其定义为一个独立的亚型，区别于其他类型的卵巢上皮性肿瘤。虽然OCCC确诊时分期一般较早(多为I期)，但较同期浆液性腺癌预后明显不良。OCCC常伴有子宫内膜异位症(endometriosis，EM)和其他恶性上皮性肿瘤，其特点为对传统化疗药物不敏感且容易复发【l捌。据