eswan序列对前列腺癌与前列腺增生鉴别诊断的价值

eswan序列对前列腺癌与前列腺增生鉴别诊断的价值

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时间:2019-02-03

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1、万方数据大连医科大学硕士学位论文ESWANTechniqueintheDifferentialDiagnosisofProstateCancerandProstateHyperplasiaMasterdegreecandidate:TongZibinSupervisor:ProfessorLiuAilianAssociateProfessorSunMeiyuMajor:MedicalimagingandnuclearmedicineAbstractobjeetive:ToexplorethefeasibilityoftheenhancedT2starweighte

2、dangiography(ESWAN)MRIpost—processedmultipleparametersindifferentialdiagnosisofprostatecancer(PCa)andbenignprostatichyperplasia(BPH).MaterialsandMethods:Inthisretrospectivestudy,56patientswerereviewedinourhospitalbetweenFebruary2012andJanuary2015withpathologicallyconfirmedprostatelesi

3、ons(26prostatecancer,30benignprostatichyperplasia).AllthepatientsunderwentprostateMRIexamsona3.0Tscarmer(GESignaHDxt,Mikauwee,USA)withpelvic8-channelphased—arrayreceivercoil,andtheprotocolincludingtheconventionalMRI(T1wI,T2WI),dynamiccontrast—enhancedMRI,diffusion—weightedimagingandES

4、WANMRI.Theimageswerepost-processedusing.FuntoolsoftwareonaGEAW4.4workstation,thenthemagnitude,phaseandR2宰mapsandsignalintensity-time(SI—T1curvewereobtained.TheR2牵andphasevaluesofeachlesionregionwereobtainedwiththere百onofinterestmanuallycircled.Theauthorandaseniorabdominalradiologist,e

5、achunawareofthepathologyresults,reviewedandrecordedallofthesize,thelocationandthesignalintensitiesofallthelesions,andwhethertherewasmetastasis(pelviclymphnodes,pelvicbone).Theyobservedasfollows:①the4万方数据大连医科大学硕士学位论文characteristicsofTIWI,T2WI,DWl.@thecharacteristicofSI-TcurvesofDCE—MRI

6、.⑨theintratumoralsusceptibilitysignalintensity(ITSS)ofphasemaps(thedotted.1inearlowsignalintensitywhichthediameterofthelesionwasmorethan5mmdefinedashemorrhage,butthelinearlowsignalintensityoncontinuouslevelsdefinedastinyveins).ForthePCapatients,theROIswereplacedonthesolidpartofthelesi

7、on(choosethelargestonethroughmultiplelesions),including2/3ofthetumorareabytwoobserverscombinedthesurgicalpathologyresulsandtheMRIimages(hypointenseT2WIsignals,hyperintenseDWIsignals,andsignificantlyenhancedwithDCE—MRI).ForBPHpatiens,theROIsshouldalsocover2/3ofthelesionregion,andchoose

8、50-70

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