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ID:32286303
大小:2.68 MB
页数:40页
时间:2019-02-02
《代谢综合征对腹型肥胖、动脉粥样硬化、外周动脉疾病的影响》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、2006级硕士学位论文代谢综合征对腹型肥胖、动脉粥样硬化、外周动脉疾病的影响代谢综合征对腹型肥胖、动脉粥样硬化、外周动脉疾病的影响摘要目的:探讨代谢综合征(MS)对腹型肥胖、动脉粥样硬化、及外周动脉疾病的影响。方法:选取2008年12月至2009年4月在广西医科大学第五附属医院体检部进行健康体检的194名体检者进入研究,其中代谢综合征(MS)体检者63例,非MS体检者131例,根据2005年国际糖尿病联盟MS全球共识定义中国标准分为代谢综合征组(MS组)和非代谢综合征组(non.MS组),测定相关的人体测量学指标、空腹血生化检查、踩臂脉博波速度、踝臂指数和经超声测量的腹部皮
2、下脂肪厚度及内脏脂肪厚度。结果:(1)MS组WT、BMI、WC、HR、SBP、MAP、DBP、PP、FPG、FPI、HOMA-IR、CRP、TC、TG、ApoB、SFr、Ⅵ玎、baPWV均高于non—MS组(p0.05);(2)V兀’依次与WT、WC、BMI、SFT、TC、TG、UA、SBP、MAP、DBP呈正相关(p3、、HR、SBP、MAP、DBP、PP、FPG、HOMA-IR、LDL.C呈正相关(p4、.1%,MS组腹型肥胖、动脉粥样硬化、外周动脉疾病检出率显著高于non.MS组(p值分别为5、00),诊断敏感度90.0%,特异度76.9%,诊断切点值是1391cm/s;男性是0.717(95%可信区间0.582.0.852;p=0.006),诊断敏感度91.3%,特异度57.6%,诊断切点值是1385cm/s。结论:内脏脂肪厚度、踝臂脉搏波速度、踝臂指数与MS组分密切相关。MS促进内脏脂肪储积,并增加动脉粥样硬化和外周动脉疾病的患病风险。内脏脂肪储积增加和踝臂脉搏波传导速度升高是良好的MS预测因子。关键词:代谢综合征,内脏脂肪厚度,踝臂脉搏波速度,踝臂指数,超声检查,ROC曲线2006级硕士学位论文代谢综合征对腹型肥胖、动脉粥样硬化、外周动脉疾病的影响EFFEC6、TOFMETABoLICSYNDROMEoNABDOMINALOBESITY,ARTERYATHEROSCLEROSIS,PERIPHERALARTERIALDISEASEABSTRACTObjective:Toinvestigatewhethermetabolicsyndrome(MS)hasaneffectonabdominalobesity,arteryatherosclerosis,peripheralarterialdisease.Methods:194physicalexamineesinthehealthexaminationdepartmentofLiuzh7、ouPeople’SHospitalwereselectedtoenterthestudy,accordingto2005IDFworldwideconsensusdefinitionofMSChinesestandards,allparticipantsweredividedintotheMSandnon—MSgroup,eachgroupincluded63casesand131casesrespectively.Anthropometicandmetabolicparameters,brachial—ankl
3、、HR、SBP、MAP、DBP、PP、FPG、HOMA-IR、LDL.C呈正相关(p4、.1%,MS组腹型肥胖、动脉粥样硬化、外周动脉疾病检出率显著高于non.MS组(p值分别为5、00),诊断敏感度90.0%,特异度76.9%,诊断切点值是1391cm/s;男性是0.717(95%可信区间0.582.0.852;p=0.006),诊断敏感度91.3%,特异度57.6%,诊断切点值是1385cm/s。结论:内脏脂肪厚度、踝臂脉搏波速度、踝臂指数与MS组分密切相关。MS促进内脏脂肪储积,并增加动脉粥样硬化和外周动脉疾病的患病风险。内脏脂肪储积增加和踝臂脉搏波传导速度升高是良好的MS预测因子。关键词:代谢综合征,内脏脂肪厚度,踝臂脉搏波速度,踝臂指数,超声检查,ROC曲线2006级硕士学位论文代谢综合征对腹型肥胖、动脉粥样硬化、外周动脉疾病的影响EFFEC6、TOFMETABoLICSYNDROMEoNABDOMINALOBESITY,ARTERYATHEROSCLEROSIS,PERIPHERALARTERIALDISEASEABSTRACTObjective:Toinvestigatewhethermetabolicsyndrome(MS)hasaneffectonabdominalobesity,arteryatherosclerosis,peripheralarterialdisease.Methods:194physicalexamineesinthehealthexaminationdepartmentofLiuzh7、ouPeople’SHospitalwereselectedtoenterthestudy,accordingto2005IDFworldwideconsensusdefinitionofMSChinesestandards,allparticipantsweredividedintotheMSandnon—MSgroup,eachgroupincluded63casesand131casesrespectively.Anthropometicandmetabolicparameters,brachial—ankl
4、.1%,MS组腹型肥胖、动脉粥样硬化、外周动脉疾病检出率显著高于non.MS组(p值分别为5、00),诊断敏感度90.0%,特异度76.9%,诊断切点值是1391cm/s;男性是0.717(95%可信区间0.582.0.852;p=0.006),诊断敏感度91.3%,特异度57.6%,诊断切点值是1385cm/s。结论:内脏脂肪厚度、踝臂脉搏波速度、踝臂指数与MS组分密切相关。MS促进内脏脂肪储积,并增加动脉粥样硬化和外周动脉疾病的患病风险。内脏脂肪储积增加和踝臂脉搏波传导速度升高是良好的MS预测因子。关键词:代谢综合征,内脏脂肪厚度,踝臂脉搏波速度,踝臂指数,超声检查,ROC曲线2006级硕士学位论文代谢综合征对腹型肥胖、动脉粥样硬化、外周动脉疾病的影响EFFEC6、TOFMETABoLICSYNDROMEoNABDOMINALOBESITY,ARTERYATHEROSCLEROSIS,PERIPHERALARTERIALDISEASEABSTRACTObjective:Toinvestigatewhethermetabolicsyndrome(MS)hasaneffectonabdominalobesity,arteryatherosclerosis,peripheralarterialdisease.Methods:194physicalexamineesinthehealthexaminationdepartmentofLiuzh7、ouPeople’SHospitalwereselectedtoenterthestudy,accordingto2005IDFworldwideconsensusdefinitionofMSChinesestandards,allparticipantsweredividedintotheMSandnon—MSgroup,eachgroupincluded63casesand131casesrespectively.Anthropometicandmetabolicparameters,brachial—ankl
5、00),诊断敏感度90.0%,特异度76.9%,诊断切点值是1391cm/s;男性是0.717(95%可信区间0.582.0.852;p=0.006),诊断敏感度91.3%,特异度57.6%,诊断切点值是1385cm/s。结论:内脏脂肪厚度、踝臂脉搏波速度、踝臂指数与MS组分密切相关。MS促进内脏脂肪储积,并增加动脉粥样硬化和外周动脉疾病的患病风险。内脏脂肪储积增加和踝臂脉搏波传导速度升高是良好的MS预测因子。关键词:代谢综合征,内脏脂肪厚度,踝臂脉搏波速度,踝臂指数,超声检查,ROC曲线2006级硕士学位论文代谢综合征对腹型肥胖、动脉粥样硬化、外周动脉疾病的影响EFFEC
6、TOFMETABoLICSYNDROMEoNABDOMINALOBESITY,ARTERYATHEROSCLEROSIS,PERIPHERALARTERIALDISEASEABSTRACTObjective:Toinvestigatewhethermetabolicsyndrome(MS)hasaneffectonabdominalobesity,arteryatherosclerosis,peripheralarterialdisease.Methods:194physicalexamineesinthehealthexaminationdepartmentofLiuzh
7、ouPeople’SHospitalwereselectedtoenterthestudy,accordingto2005IDFworldwideconsensusdefinitionofMSChinesestandards,allparticipantsweredividedintotheMSandnon—MSgroup,eachgroupincluded63casesand131casesrespectively.Anthropometicandmetabolicparameters,brachial—ankl
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