欢迎来到天天文库
浏览记录
ID:32251431
大小:3.45 MB
页数:54页
时间:2019-02-02
《针灸、大黄对重度颅脑损伤患者脑脊液中il6、il10表达的影响》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、江苏大学硕士学位论文降,1、2d脑脊液中IL一10浓度均高于同期对照组,3、5d低于同期对照组,但与对照组相比无显著性差异(P>O.05);第二部分:三组的ICP统计结果示:(1)针灸组和对照组的ICP都是第2d达高峰,3、5d持续下降,大黄治疗组的ICP从第1d起开始下降,2、3、5d继续下降。(2)大黄治疗组的ICP水平明显降低与同期对照组比较有显著性差异(PO.05);(4)三组间同期的GCS评分、住院期间的昏迷时间及其出院时的GOS评分之间的差别互相比较无显著性差异(
2、胗0.05)。结论:1.针灸可使重度颅脑损伤后脑脊液中升高的IL-6含量下降,与对照组相比有显著差异,对IL—lO的影响无显著意义。2.大黄能降低重度颅脑外伤患者脑脊液中IL-6的浓度,但与对照组相比差异无显著意义,对IL-IO的影响无显著意义,同时发现大黄能明显降低颅内压。关键词重度颅脑损伤,CSF,IL一6,IL一10,针灸,大黄ll江苏大学硕士学位论文ABSTRACTObjective:Toinvestigatetheeffectofaccupunctureandrhubrabonseverelytraumaticbraininjury(S-
3、TBOinpatientsbasedoncytokine.Methods:Thefirstpart:Fifty—sevencaseswithSTBlwererandomlyividedintofollowinggroups:theaccupuncturetreatmentgrouptreatedbytheconventionalwesternmedicinetherapycombinedwithaccupunctureLaogong、LiduiandYongquan,therhubrabtreatmentgrouptreatedbytheconve
4、ntionalwestemmedicinetherapywithrhubrab,thecontrolgrouptreatedwithconventionalwestemmedicinetherapy.A3mLcerebro—spinalfluid(CSF)samplefromeachpatientwasdrawnonthe1st,2nd,3rdand5thdayaftertheinjury,andwhichwasseparatedbycentrifugationimmediatelyandwasstoredin-70"Crefrigerator.T
5、heconcentrationofinterleukin一6(IL一6)andinterleukin一1O(IL一10)inCSFofpatientsweremeasuredbyPartecFlowcytometery(FCM).Thepurposeofthesecondpartwastocollectthewholeclinicalindexofallenrolledpatients.Dateswereexpressedasmean+SD(夏_+s),andanalyzedbyIndependent—samplesTtest,whatismore
6、thesignificiencelevelwasP7、velofIL一6inCSFwasreachedthehighestlevelonthe1st,anddecreasedonthe2nd,3rdand5thday.③TheleveloflL.10intheaccupuncturetreatmentgroupwashigheronthe1Sday,butwasloweronthe2nd,3rdand5thdaysthanthecontrolgrouprespectively.④IntherhubrabtreatmentgroupthelevelofIL一10inCSFwasreachedthehig8、hestlevelonthe2ndday,theydecreasedonthe3rdandthe5ndday,江苏大学硕士
7、velofIL一6inCSFwasreachedthehighestlevelonthe1st,anddecreasedonthe2nd,3rdand5thday.③TheleveloflL.10intheaccupuncturetreatmentgroupwashigheronthe1Sday,butwasloweronthe2nd,3rdand5thdaysthanthecontrolgrouprespectively.④IntherhubrabtreatmentgroupthelevelofIL一10inCSFwasreachedthehig
8、hestlevelonthe2ndday,theydecreasedonthe3rdandthe5ndday,江苏大学硕士
此文档下载收益归作者所有