原发性纵隔生殖细胞瘤的手术治疗

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1、中国医学科学院协和医科戈学硕士毕业论曼而1例手术后再次复发行手术治疗。恶性生殖细胞瘤的5年生存率为30．8％，已证实死亡的19例，其中2例死于与手术有关的原因。结论原发性纵隔生殖细胞瘤除囊性成熟型畸胎瘤术前易于正确诊断，而其他类型不易正确诊断，往往易误诊为纵隔其他肿瘤，对术前诊断未明确诊断的，手术切除往往足治疗的重要手段。纵隔fF殖细胞瘤的治疗需根据不同患者的具体情况，选择／{i同的治疗方法。【关键词】原发性纵隔生殖细胞瘤；诊断；治疗；预后。原发性纵隔生殖细胞瘤的手术治疗———_!璺垦兰塑兰堕塑童垦苎苎兰璺主兰兰堡叁SurgicalTreatmentof103cases

2、ofprimarygermcelltumorsofthemediastihum(abstract)【ABSTRACT】OBJECTIVETounderstandthecnnicaicharacteristicsofprimarygermcelltumorsandtofindoutrationalsurgicaltreatment．METHODSfromJanuary1990toJuly2003，103patientswereadmittedintoDepartmentofThoracicSurgery，CancerInstitute(Hospital)．ChineseA

3、cademyofMedicalSciences．PekingUnionMedicalCollege．theclinicalmatericalsof103casessurgicaltreatedpatientswithprimarygermcelltumorsofmediastihumwereretrospectivelyanalyzedSurgicalremovalwasdonefora11patients．A1thoughmatureteratomasarehist0109icallybenign，theymaypresentdifficultsurgicalprob

4、]emsbecauseoftheVitalstructureinvolred．59casesofthesepatientswereperformedcompletelYtumorextirpatiOilalone．24casesrequired10bectomyorwedgeresectionorsegmentectomywithtumorextirpation，13patientsreceivedpericardectomywithtumorextirpation，onepatientunderwenttotalpneumonectomyresection，media

5、stinoscopicexaminationwasapplledtoonepatient，onepatientreceivedthoracostomy，threepatientSwhichadherenttoadjacentvital原发挂纵隔生殖细胞瘤的手术治疗——一一一!璺垦兰翌兰堕竺童垦登苎兰堡主兰兰笙圭structure，wereunderwentvascularorphrenicnerveresectionthreepatientswereperformedpleurectomy．93casesthosepatientshadcompletelyresecte

6、d(90．1％)，patientsunderwentsalvageresection．twopatients，withlocalrecurrenceatinitialsite，requiredthoracicsurgicalprocedures．5ofthesepatientsreceivedpreoperativechemotherapy．Thosepatientswhichdiagnseteratoma，don’trequirefurthertherapytheotherpatientsunderwentsurgicalradicalresectionfollowe

7、dbycbemoradiationtherapyandchemotherapyorradiotherapyRadiationiSused，withradiationdoseoflOtoTOGychemotherapybasedonPVB、PEB、CEBregimenwasemployedKaplan—MeiermethodwasusedinsurvivedanalysiS．RESULTacorrectpreoperativediagnosiSobtainedinOillY78casesofthe103cases，67sufferedfro