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ID:32214809
大小:2.55 MB
页数:38页
时间:2019-02-01
《循环肾素--血管紧张素--醛固酮系统与2型糖尿病证型相关性的分析》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、AbstractObjective:ToinvestigatetherelationshipofserumangiotensinII(AngII)andaldosterone(ALD)withglycosylatedhemoglobin(HbAlc),ageandtheotherbiochemicalindexinpatients谢tll够pe2diabetes.Alsowediscussesthecorelationbetweenrenin-angiotensin·aldosteronesystem(RAAS)anddiabeticperipheralne
2、uropathy.Inaddition,weobservetherelationshipbetweenRAASandyindeficiencyandheatsyndrome,phlegm-dampnesssyndrome,bloodstasissyndromewithType2diabetespatients。ThisstudyCallprovidecertainobjectivereferencebasisforthestudyofTCMsyndromeoftype2diabetes.Methods:Sixty—threepatientwithtype2d
3、iabetesrecivedmeasurementsofAnglI,AL2D,HOMA-IR,fastingbloodglucose(FBG),fastinginsulin,HbA1c,homeostasismodelofassessmentforinsulinresistenceindex(HOMA—IR),triglyceride(TG),totalcholesterol(TC),lowdensitylipoproteincholesterol(LDL—c),ALDandAnglI.Thenallpatientswererespectivelydivid
4、edintotwogroups:hypertensiongroup(n=21)andnon-hypertensiongroup(n=42),high-HbA1C(h-HbAlc)group(n=33)andnon—high—HbAlc(non—h—HbAlc)group(n=30),elderlygroup(n=33)andnon—elderlygroup(n=30),diabeticperipheralneuropathy(DPN)groupandnon—DPNgroup.Allthepatientsdiabetesdialecticalpointstyp
5、e:yindeficiencyandheatsyndromegroup(n=27)andnon-yindeficiencyandheatsyndromegroup(n=36),phlegm-dampnesssyndromegroup(n=34)andnon—phlegm—dampnesssyndromegroup(n=29),bloodstasissyndromegroup(n218)andnon—bloodstasissyndromegroup(n=45).Therelationshipamongthebiochemicalindexwasanalyzed
6、.Results:TherewasapositivecorrelationofthelevelsoftheALD,Ang11withHbAlc.Otherwise。ThelevelsofALDandAng11werenegativelycorrelatedwithageinpatients、舫t}Itype2diabetes.ThelevelofAng11waspositivelycorrelatedwithFBGALDandAngIIinhypertensiongroupandnon—hypertensiongroupwasnotsignificantly
7、different..However,FBG,HOMA—IR,ALD,AngIIinh-HbAlcgroupweresignificantlyhigherthaninnon-h—HbAlcgroup.Low-densitylipoproteinCholesterol(LDL—C)、ALDandAngIIinelderlygroupwerelowerthaninnon—elderlygroup.MultipleregressionanalysisshowedthatAng11wasstillinasignificantlypositivecorrelation
8、withHbAlc,andALDwasinasign
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