血浆五聚素3在冠心病与高血压患者中的临床意义

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1、AbstractResults1．398patientsfromthedepartmentofcardiologyoftheFirstAffiliatedHospitalofZhengzhouUniversity，excludedpatients249cases(62．56％)，theremaining149casesmetthestudycriteriawereselected；98positivecasesofcoronaryangiography,54malesand44females，averageage56．4士8．4yearsold，ofwhich46cas

2、eswithhypertension(groupA)，26malesand20females，averageage56．14-7．5yearsold，52caseswithouthypertension(groupB)，28malesand24females，averageage56．64-8．0yearsold，ofwhichcoronaryangiographyofcoronarystenosislessthan50％，andclinicalsymptomsexcludecoronaryheartdiseaseandhypertension，51casestheco

3、ntrolgroup(groupC)，25malesand26females，averageage(55．44-7．2)yearsold．2．Thegender’age，bodymassindex，smokinghistory,drinkinghistory,platelet，HDL-C，ALB，BUN，ScrandfastingbloodglucosehavenoobviousdifferencebetweengroupA，groupBandgroupC妒>0．05)；theLDL·C，TGTC，cTnI，hs—CRPlevelsofgroupAandgroupBis

4、higherthangroupc,thedifferenceWasstatisticallysignificant俨<0．05)．theLDL-C，TGTC，cTnI，hs-CRPlevelsindicatorsnosignificantdifferencebetweengroupAandgroupB(P>0．05)．3．Pentraxin3(PTX3)levelaftertakinglogarithmremainsnormaldistribution，thepentraxin3(PTX3)levelofcoronaryheartdisease(CHD)alongwit

5、hhypertensiongroup(groupA)isoverthanthecontrolgroup(groupC)妒

6、ionanalysisshowed：PTX3levelswithLDL-C(r=0．136，P=O．014)andcTnI(r=0．249，P=0．004)werepositivelycorrelated；PTX3levelsandHDL．C(r=．O．184，P=0．032)werenegativelycorrelated．GensiniscorehadnosignificantcorrelationwithPTX3；Gensiniscorewithhs-CRP(r=0．239，P=0．018)andcTnI(r=0．274，P=0．013)werepositivel

7、yVIAbstractcorrelated．Conclusions2．Pentraxin3levelswereelevatedinpatientswithcoronaryheartdisease，andwerefurtherincreasedforpatientswithhypertension．TherewasnosignificantcorrelationbetweenPTX3levelsandtheseverityofcoronarystenosis．KeywordsPentraxin3；coronaryheartdisease；h