能谱ct在肺癌病理分型与纵隔淋巴结转移评估中的初步应用分析

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1、万方数据天津医科大学硕士学位论文谱指标和淋巴结短径标准，可提高诊断准确度。利用能谱CT评估非小细胞肺癌淋巴结转移具有临床应用价值。关键词：肺癌断层摄影术x线计算机能谱成像淋巴结肿瘤转移万方数据天津医科大学硕士学位论文SectionIAbstractEvaluationofhistologicclassificationoflungcancer：initialexperiencewithspectralCTimagingobjective：TodetecttheusefulnessofgemstonespectralCTinhistologicclassi

2、ficationoflungcancer．Methods：71patientswithprimarylungcancerconfirmedbyhistopathologywereretrospectivelyanalyzed．Theyallgotcontrast-enhancedgemstonespectralimagingscanningbeforetherapy．Amongthe71casesoflungcancer,27casesweresquamouseellcarcinoma，34caseswereadenocarcinoma，andtheot

3、her10casesweresmalleelllungcancer．Theiodineconcentrations(IC)ontheiodine-basedmaterial·decompositionimages，theCTvaluesatdifferentmonokiloelectronvolt(keV)andthespectralattenuationcurveweremeasuredinthelesionsrespectively．Theslopesofthecurveandthenormalizediodineconcentration(NIC)

4、valueagainsttheaortawerecalculated．Dataamongdifferenthistologicaltypesoflungcancerwereanalyzedcomparativelybyanalysisofvariance．TheROCcurveofthesespectralparameterswerecalculatedandthediagnosticvaluewereassessed．Results：Therewerenosignificantdifferencesbetweenthesquamouscellcarci

5、nomaandadenocarcinomaintheCTvalues，theslopes，ICvalueandNICvalue(P=1．000)．TheNICshowedsignificantdifferencesbetweensmallcelllungcancer(SCLC)andsquamouscellcarcinoma(0．25+0．10&0．34+0．10，P=O．034)oradenocarcinoma(0．25+0．10&0．32+0．11．P=O．045)．Thebestcut-offpointofNICindiagnosingSCLCwa

6、s0．2508．Thesensitivity，specificity，positivepredictivevalueandnegativepredictivevalueandaccuracywas86％，70％，95％，50％and78％respectively．Conclusion：SquamouscellcarcinomaandadenocarcinomaCannotbedifferentiatedbygemstonespectralCq、．NIChasacertainvalueindifferentialdiagnosisofSCLCandNSCL

7、，C．Keywords：lungcancerhistologyclassificationspectralimagingtomographyX—raycomputedIV万方数据天津医科大学硕士学位论文SectionIIThevalueofspectralCTinevaluationoflymphnodesmetastasisoflungcancerObjective：TodetecttheusefulnessofgemstonespectralCTindiagnosisoflymphnodemetastasisoflungcolacer．Methods

8、：40mediastinallymphnodesfrom27casesofnon