非小细胞肺癌纵隔淋巴结转移 CT 与病理的一致性研究.pdf

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1、现代肿瘤医学2014年8月第22卷第8期MODERNONCOLOGY，Aug．2014，VOL．22，NO．08．．．胸部肿瘤．：．非小细胞肺癌纵隔淋巴结转移CT与病理的一致性研究张锋，石静滨TheconsistencyofCTandpathologyinnon——smallcelllungcancermediastinallymphnodemetastasisZhangFeng，ShiJingbinSecondAffiliatedHospitalofDalianMedicalUniversity，Liaonin

2、gDalian116023，China．【Abstract】0bjective：ToexploretheconsistencyofCTandpathologyinnon—smallcelllungcancer(NSCLC)mediastinallymphnodemetastasis．Methods：Selected178NSCLCpatientswhoreceivedthesurgicaloperationandCTscanbeforeoperationinthoracicsurgeondepartmentoft

3、heSecondAfiliatedHospitalofDalianMedicalUniversityfrom2009to2011．107ofthemshowedtheabnorlnalmediastinallymphnode．75malesand32females．Age：42—80yearsold，themedianage62yearsold．RecordedthenumberoflymphnodeonCTandpathologicalpositivenumber，thencalculatedthemetast

4、asisrate，andobservedthetruepositive，truenegative，falsepositive，falsenegative，sensitivi—ty，specificity，positivepredictivevalue，negativepredictivevalue，accuracy．Results：Therelationshipbetweenlymphnodesizeandmetastasisrate：Themetastasisratewas17．6％whenlength<10m

5、m．themetastasisratewas31．7％whenlength10—14mm，themetastasisrate58．8％whenlength15—19mm，themetastasisrate93．9％whenlength>／20mm．Length≥15mmwaslymphnodemetastasis：falsepositive21cases．falsenegative24cases．Sensitiitywas57．9％，specificity82．6％，positivepredictivevalue

6、61．1％，negativepredictivevalue80．6％，accuracy74．7％．Ac·cordingtothedividedstandard：Falsepositive15cases，falsenegative23cases．Sensitivity59．6％，specificity87．6％，positivepredictivevalue69．4％，negativepredictivevalue82．2％，accuracy78．7％．Conclusion：Alongwiththeincrease

7、oflymphnodelength，themetastasisrateisincreasinggradually．Thelymphnodemetastasisrateofadenocarcinomaishigherthansquamouscarcinoma，evenwhenthelymphnodelengthissmal1．Thelymphnodeme-tastasisratewhenCT>2abnormallymphnodeishigherthan≤2abnormallymphnode．evenwhenthel

8、ymphnodelengthissmal1．【Keywords】NSCLC；CT；lymphnodemetastasis；lymphnodelength；pathologicaltypeModemOncology2014，22(08)：1807—1810【摘要】目的：探讨非小细胞肺癌(NSCLC)纵隔淋巴结转移cT与病理的一致性，为靶区勾画提供依据。方法：选择2009年1