【5A版】乙肝两对半的解读.ppt

《【5A版】乙肝两对半的解读.ppt》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。

1、乙肝两对半的解读Secondliverhalf-and-halhinterpretatino乙肝两对半的定义TheDefinitinoOfSecongLiverTwoHalf-and-Half大三阳和小三阳Big3thisworldandsmall3thisworld乙肝的传播途径Thetransmissionwayofsecondliver*对乙肝的误解Misunderstandingofhepatitisb什么是乙肝两对半乙肝两对半是国内医院最常用的乙肝病毒(HBV)感染检测血清标志物。(Secondlivertwohalf-and-halfisthemostcommonlyused

2、indomestichospitalofhepatitisbvirus(HBV)infectiondetectionserummarker)①乙肝表面抗原（HBsAg）②乙肝表面抗体（抗-HBs）③乙肝e抗原（HBeAg）④乙肝e抗体（抗-HBe）⑤乙肝核心抗体（抗-HBc）测定两种抗原和三种抗体，也就是俗称的“两对半”。Determinationoftwokindsofantigensandthreekindsofantibody,alsoknownasthe"twohalf-and-half".大三阳和小三阳Big3thisworldandsmall3thisworld“大三阳”是指

3、“乙肝两对半”化验结果为表面抗原、e抗原和核心抗体检测均是阳性。一般说明病毒复制水平高、传染性强。"Big3thisworld"refersto"secondlivertwohalf-and-half"testresultsforthesurfaceantigen,eantigenandcoreantibodytestsarepositive.Generaldescriptionswithhigh-levelviralreplicationandinfectivity.“小三阳”是指“乙肝两对半”化验结果为表面抗原、E抗体和核心抗体检测均是阳性。一般说明病毒复制水平相对较低、传染弱。Wh

4、atissmall3thisworld"small3thisworld"refersto"secondlivertwohalf-and-half"testresultsforthesurfaceantigen,Eantibodyandcoreantibodytestsarepositive.Generaldescriptionsviralreplicationlevelisrelativelylowandweak.可见大三阳和小三阳的区别主要在病毒复制活跃程度上，但并不表示“大三阳”一定比“小三阳”病情严重，临床研究证实，有些小三阳患者更容易转化为肝癌。在治疗上，如果是乙肝患者且HBVD

5、NA含量高，大三阳和小三阳的区别不大，都要以抗病毒治疗为主，辅助抗炎保肝，抗纤维化治疗。Visiblebig3thisworldandsmall3thisworlddifferenceismainlyintheviralreplicationactivity,butitdoesn'tmeanthe"big3thisworld"than"small3thisworld"thediseaseissevere,clinicalstudieshaveconfirmedthatsomesmall3thisworldaremorelikelytobeconvertedintolivercancerp

6、atients.Intreatment,ifishepatitisbpatientsandhbvdnacontenthigh,thedifferencebetweenbig3thisworldandsmall3thisworldisnotbig,togiveprioritytowithantiviraltherapy,anti-inflammatory,protectingliver,auxiliaryantifibrosistreatment.乙肝的传播途径Thetransmissionwayofsecondliver血液传播（Bloodtransmission)：如输入被感染的全血、

7、血浆、血清或其它血制品，或其他血源性注射传播。Suchasinputofwholeblood,plasma,seruminfectedorotherbloodproducts,orotherblood-bornespreadofinjection性传播(Sexuallytransmission)：性滥交、同性恋和异性恋之间的亲密性行为是重要的乙肝病毒传播途径，这种传播亦包括家庭夫妻间的传播，夫妻之间的无防御措施的性行为传播率大概在1