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1、天津医科大学硕士学位论文grayinthecytoplasm,comparedwithNC(47.21±8.72)group,DMgroup(89.84±10.71)andRGZgroup(61.25±8.13)grayvalueincreased,thedifferenceswerestatisticallysignificant(P<0.01).7.ComparisonofchangesofhepaticstellatecellThehepaticstellatecelllocatedbetweenthespaceofDisseandlivercells
2、,livercellsgoldchloridestainingmakesthehepaticstellatecellswerepurplebrown,lightgraybackground.Bycountinghepaticstellatecellsathighmagnification,comparedwithNCgroup(2.75±0.21),theDMgroup(7.19±0.45)hepaticstellatecellsnumberwereincreased(P<0.05),andcomparedwithDMgroup,RGZgroup(4.93±
3、0.48)hepaticstellatecellsnumweredecreased(P<0.01).8.ComparisonofchangesofcollagenfibresInNCgroup,livertissueblueshadedaccidentallyfoundinthewall,onlyverysmallamountsofcollagendepositedinthecentralveinwall;WhileinDMgroup,hepaticlobuleslosttheirnormalstructures,therewerealargenumbero
4、fcollagenfibers,depositingfromcentralveinandportalareatothesurroundingextension.InRgzgroup,thecollagenfibersreducedinportalarea,comparedwithDMgroup.TheamountofcollagenconnectivetissuecoveringthepercentageofNCgroupwas(3.19±0.75),whencomparedwithNCgroup,DMGroup(15.87±0.63)percentagew
5、asincreasedsignificantly.comparedwiththeDMgroup,RGZgroup(10.06±0.54)detectedintheportalareavisiblefibrousseptawasreduced(P<0.05).9.ComparisonofcollageninliveramongthreegroupsofratsComparedwiththeDMgroup(134.54±18.78mg/g),NCgroup(64.52±21.51mg/g)hadlowerthecontentofcollagen(P<0.01);
6、RGZgroup(91.59±10.75mg/g)ishigher(P<0.01).10.ComparisonoftheexpressionofIL-17ComparedwiththeDMgroup(0.520±0.021),NCgroup(0.129±0.045)(P<0.01)andRGZgroup(0.235±0.034)hadhigherintensityofpositiveexpressionofIL-17(P<0.01).11.ComparisonoftheexpressionofBcl-xLComparedwiththeDMgroup(0.24
7、2±0.041),NCgroup(0.613±0.014)(P<0.05)andRGZgroup(0.369±0.048)hadhigherintensityofpositiveexpressionVII万方数据天津医科大学硕士学位论文ofBcl-xL(P<0.01).Conclusion1.Indiabetesratsthehepaticlobulesweredisorder,thehepatocyteswereswelling,collagencontentincreasessignificantly.2.Indiabetesratsthehepatic
8、stellatecellswereactivated