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1、临床药师干预清洁手术围手术期预防性应用抗菌药物的对比分析宋培光,董艳,黄馨,刘赞,辛岩岩(安徽省淮北矿工总更院,安徽淮北235000)摘要:目的临床药师对医院三种I类清洁手术(甲状腺手术、乳腺手术、疝气修补术)抗菌药物预防应用的干预效果评价。方法分别抽取普外科2012年一6月份出院的三种I类清洁手术干预前病例189例和2012年7—12月份出院的三种I类清洁手术干预后病例165例,对抗菌药物预防应用的临床合理性进行评价。结果经过临床药师干预,清洁手术圉术期患者预防应用抗菌药物在临床适应证、药物的选择、用法用量、用药时机、给药途径、溶媒选择等各方
2、面较干预前均得到明显改善。结论临床药师对围术期预防应用抗菌药物进行干预的方法是可行和有效的,能促进临床合理使用抗菌药物,优化医疗资源使用,对促进抗菌药物临床安全、有效、经济的应用可起到良好的效果。关键词:临床药师;抗菌药物;清洁手术;合理用药干预doi:10・3969/j・issn・1009—6469・2014・丄0・062Interventioninprophylacticapplicationofantibacterialsbyclinicalphannacistsduringperi-operativeperiodofcleaningop
3、erationSONGPei-guang,DONGYan,HUANGXin,etal(HuaibeiMiners'GeneralHospital,Huaibei,Anhui235000,China)Abstract:ObjectiveToassesstheeffectofclinicalpharmacisfsinterveningintheantibioticmedicineapplicationforthyroidsurgery,breastsurgeryandherniarepairsurgery(3cleaningoperations).
4、MethodsAtotalof189cases(beforetheintervention)whichunderwenttheabovethreecleaningoperationsintheDepartmentofGeneralSurgeryandweredischargedinthetimeperiodfromJan.2012toJun.2012fromHuaibeiMiners'GeneralHospitalwerecollected,and165casesdischargedfiomhospitalfromJul.2012toDec.2
5、012(aftertheintervention)werechosen.Therationalityofpreventativeapplicationforantibioticswasanalyzed.ResultsAftertheinterventionsbytheclinicalpharmacists,thepreventativeapplicationofmedicineforcleaningsurgerywasimprovedobviouslycomparedwithpre-interventioninaspectsoftheindic
6、ations,medicineselection,dose,timingformedication,routeofadministration,themenstruumofmedicineselection.ConclusionsTheinterventioninthepreventativeapplicationofantibioticsbytheclinicalpharmacistsisfeasibleandeffective,whichcanimprovetherationalapplicationofantibiotics,decrea
7、semedicalcost,andpromotesafe,effective,andeconomicaluseofantibiotics.Keywords:clinicalpharmacists;antibiotics;cleaningsurgery;rationalmedicineintervention清洁手术,也称I类切口手术,其手术视野为人体的无菌部位,按照《抗菌药物临床应用指导原则》的相关规定,若患者无高龄、异物植入、糖尿病等高危因素,医师手术吋严格执行无菌操作,般情况下无需预防性使用抗菌药物[1]。甲状腺手术、乳腺手术和疝修补术是外
8、科常见的【类手术,手术部位清洁。但是,在临床医疗实际工作中,由于医师的专业缺陷、防范医疗风险等诸多原因,通常在药品选择、用法用量、用药时机、用药疗程和