3-大豆苷元磺酸钠对离体心脏缺血再灌注损伤的保护作用

3-大豆苷元磺酸钠对离体心脏缺血再灌注损伤的保护作用

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时间:2019-01-06

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1、3-大豆昔元磺酸钠对离体心脏缺血再灌注损伤的保护作用ThesodiumsulfonatewasdamagedbytheabseneeofbloodinthebodyofthebodyprotectionTheauthor:thebellisrichxiaohailihonglianghuangzhihua,sweizengjing【abstract】objectivetousethef1owmodelofthebodyofthebodyofthebody,study3'-soybeansulfonicacid

2、sodiumtothebodyheartTheprotectiveeffectofischemicreperfusioninjury.Methodstoapplythedamagemodelofischemiareperfusioninjuryinrats,Addhighandlowdosesof3'soysulfonate(0.03,0.01mg/L)intheirrigationfluid.ThedeterminationofCoronaryf1owrate,heartrate,leftventricul

3、arsystolicpressure,leftventriculardiastolicpressurechanges・Results3'-soyglycosidesThesodiumacidcanbeusedtoincreasetheflowoftheheartaftertheischemiareperfusion,theleftventricularsystolicpressureincreases,theleftventriculardiastolicpressuredropsLowerheartrate

4、andlowerheartrate・Conclusion:thesodiumsulfonatecanincreasecoronaryartery,s1owheartrateandincreaseheartMyosystolicforcesprotectthecardiacischemiaofthebody.[keywords]3'-soybeansulfonicacidsodiumsulfonatewasdamagedbyreperfusionofbloodfromtheheart3'-daidzeinsul

5、fonatesodium,DSSisthemainChinesemedicineTheactiveingredientsoybeanglycosidesareusedtomodifyandmodifythenewsyntheticwater-solublesubstances・3'-soyglycosidesSodiumsulfonate[C15H907SNa],thestructureisshowninFIG・1,whichisawhitecrystallinepowder,whichisreplanted

6、byshenyangpharmaceuticaluniversityTheteachingandresearchroomprovidesmorethan99%purity・Thestudyshowedthat3?-soybeansulfonicacidsodiumsulfonatewasshort_1],[2],antiarrhythmia,[3],andtheeffectontherightatriumoftheguineapigContractionfeature[4]・Ourpreliminaryres

7、earchalsoshowedthattheprecursorsoybeanglycineofthe3'-soybeanglycinesulfonateDamagetomyocardialischemiareperfusionhasprotectiveeffecton[5]・Inordertoexplorewhetherthe3'-soybeansourssodiumisusedThereisalsotheroleofanti-myocardialischemiareperfusioninjury,which

8、wasdevelopedthroughtheLangendorffcardiacirrigationsystemThispaperinvestigatestheprotectiveeffectofdisinfectiveandreinfectiveinjury.FIG・1,3,-thechemicalstructureofsodiumsulfonate1equipment1drug3'-soybea

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