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1、内镜下微创诊治58例胃异位胰腺临床分析张莉敏1,2,*,樊超强1,*,赵晶京3,张传涛2,杨仕明1(400037重庆,第三军医大学:新桥医院消化科1,西南医院全军消化病研究所3;610072成都,成都中医药大学附属医院消化科2)[摘要]目的分析胃异位胰腺内镜下特点,评估内镜下黏膜切除术(endoscopicmucosalresection,EMR)和内镜下黏膜剥离术(endoscopic submucosal dissection,ESD)对胃异位胰腺的治疗价值。方法回顾性分析第三军医大学新桥医院2008年11月至2012年1
2、1月内镜下切除且病理诊断明确的58例胃异位胰腺病例资料,其中男性23例,女性35例,平均39.6(14~75)岁,包括行EMR20例和行ESD38例,总结其内镜特点,比较EMR和ESD的治疗效果。结果部分患者以上腹部隐痛、腹胀为主诉;均单发黏膜下包块,表面完整,典型者可有中心脐样凹陷,占27.59%(16/58);超声内镜发现多来源第3层,回声不均匀,有时与固有肌层分界不清,超声内镜与术后病理诊断均一致,达100%(58/58)。行EMR20例,复发率20%(4/20),无并发症;行ESD38例,无复发,2例术中出血和2例穿孔
3、。ESD与EMR治疗胃异位胰腺相比,复发率低(P<0.01),并发症发生率较高。结论超声内镜对胃异位胰腺诊断率高,ESD治疗胃异位胰腺较EMR复发率低,但并发症发生率较高。[关键词]异位胰腺;消化内镜;EMR;ESD[中图法分类号][文献标志码]ADiagnosisandminimallyinvasivetreatmentof58caseswithectopicpancreasZhangLimin,FanChaoqiang,ZhaoJingjing,ZhangChuantao,YangShiming(DepartmentofG
4、astroenterology,XinqiaoHospital,ThirdMilitaryMedicalUniversity,Chongqing,4000371;DepartmentofGastroenterology,ThehospitalaffilatedUniversityoftraditionalChineseMedicine,Chengdu,6100722;DepartmentofGastroenterology,SouthwestHospital,ThirdMilitaryMedicalUniversity,Cho
5、ngqing,400037,China3)[Abstrat]ObjectiveToanalysetheendoscopiccharacteristicsandevaluatethevalueofEMRandESDforectopicpancreasinstomach.MethodsDataof58patients(includingEMR20casesandESD38cases)withendoscopicdissectedandpathologicallyconfirmedectopicpancreaswasstudiedi
6、nourhospitalfromNovember2008toNovember2012.TosummarizethefeaturesoftheectopicpancreasandcontrasteffectofEMRandESD.ResultsTotallyof58casesinwhichthemeanageofthepatientwas39.6y(14~75y)withM/Frationof35/23rangingfrom14-75.Epigastricpainandabdominaldistensionarethecommo
7、npresentations,Mostofthelesionsdetectedwerelocatedasasinglemasswithinthestomach.Ofwhichwerecharacterizedbyprotrusion,withintactmucousmembranceandcentrallyumbilicated(27.59%,16/58).Ultrasonographyfindingswereheterogeneousandmixedechogeniclesionswithindistinctbordersi
8、nvolvingboththesecondandthirdlayersofthegastricwall,sometimeseveninvolvingthefirstandfourthlayers.20caseswereremovedbyendoscopicmucosalres