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ID:28043032
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时间:2018-12-07
《丹红注射液联合前列地尔注射液治疗慢性肾脏病的临床效果研究》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、丹红注射液联合前列地尔注射液治疗慢性肾脏病的临床效果研宄[摘要]目的探讨丹红注射液联合前列地尔注射液在慢性肾脏病患者中的临床治疗效果。方法取2015年1月〜2016年10月医院收治的慢性肾脏病患者50例,随机数字法分为对照组和观察组。对照组采用常规方法治疗,观察组联合丹红注射液、前列地尔注射液治疗,采用酶联免疫吸附试验检测两组治疗前、后肾功能及尿蛋白水平,比较两组临床疗效。结果两组治疗后2周的临床疗效率比较差异有统计学意义;观察组治疗后2周的BUN、SCr水平低于对照组;观察组治疗后血红蛋白水平高于对照组;两组治疗后2周的安全性比较差异无统计学意义。结论慢性肾脏病患
2、者在常规方法基础上联合丹红注射液、前列地尔注射液治疗效果理想,能改善患者肾脏水平,安全性较高,值得推广应用。[关键词]丹红注射液;前列地尔注射液;慢性肾脏病;肾功能;血红蛋白[中图分类号]R692[文献标识码]B[文章编号]1673-970114-0100-03[Abstract]ObjectiveToinvestigatetheclinicaleffectofDanhonginjectioncombinedwithalprostadilinjectioninthetreatmentofchronickidneydisease.MethodsAtotalof50pa
3、tientswithchronickidneydiseasewhowereadmittedtoourhospitalfromJanuary2015toOctober2016wereselectedanddividedintothecontrolgroupandtheobservationgroupbyrandomnumbermethod.Thecontrolgroupwasgivenroutinemethod,andtheobservationgroupwasgivenDanhonginjectioncombinedwithalprostadilinjection.
4、Thelevelsofrenalfunctionandurinaryproteinweremeasuredbyenzyme-linkedimmunosorbentassaybeforeandafterthetreatmentinbothgroups.Theclinicalefficacywascomparedbetweenthetwogroups.ResultsThedifferencesoftheclinicalefficacybetweenthetwogroupswerestatisticallysignificantat2weeksaftertreatment
5、;thelevelsofBUNandSCrintheobservationgroupwerelowerthanthoseinthecontrolgroupafterthetreatment;thelevelofhemoglobinintheobservationgroupwashigherthanthatinthecontrolgroupafterthetreatment;therewasnostatisticallysignificantdifferenceinthesafetybetweenthetwogroupsat2weeksaftertreatment.C
6、onclusionThetherapeuticeffectofDanhonginjectioncombinedwithalprostadilinjectioninthepatientswithchronickidneydiseaseonthebasisofconventionalmethodsisideal,whichcanimprovekidneylevelofthepatients,withahighsafety,andisworthyofpopularizationandapplication.[Keywords]Danhonginjection;Alpros
7、tadilinjection;Chronickidneydisease;Renalfunction;Hemoglobin慢性今I脏病是临床上常见的疾病,且随着人口老龄化的日益加剧,导致CKD发生率呈现上升及年轻化趋势[1]。数据报道显示[2]:美国20岁以上CKD发生率己经达到13.0%,我国发生率为10.0%,严重影响患者健康及生活。目前,临床上对于CKD有效治疗方法包括:血液透析、腹膜透析、肾移植等,但是这些治疗方法医疗费用较高,患者治疗依从性较差,难以在基层医院推广应用[31。文献报道显示[4]:将丹红注射液联合前列地尔注射液用于CKD患者中效果理想,该方
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