丁苯酞联合前列地尔注射液治疗后循环缺血性眩晕的临床效果

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1、丁苯酞联合前列地尔注射液治疗后循环缺血性眩晕的临床效果［摘要］目的观察丁苯酞联合前列地尔注射液治疗后循环缺血性眩晕的临床效果。方法收集2016年1〜10月于鄂东医疗集团黄石市中心医院接受治疗的110例后循分h缺血性眩晕患者作为观察对象，按照随机数字表法将其分为对照组和观察组。在常规治疗的基础上，对照组给予前列地尔注射液，观察组在对照组的基础上联合丁苯酞治疗，疗程2周。疗程结束后，比较两组临床疗效、治疗前后后循环血流速度及不良反应发生情况。结果眩晕临床疗效显示，观组总有效率显著高于对照组，差异有统计学意义。治疗前，两组患者基底动脉、左椎动脉、右椎动脉血流速度比较，差异无统计学意义；治

2、疗后两组上述参数均较治疗前显著加快，且观察组基底动脉、左椎动脉、右椎动脉血流速度明显快于对照组，组间比较差异均有统计学意义。治疗过程中，无严重不良反应病例，对照组和观察组不良反应发生率比较差异无统计学意义。结论丁苯酞联合前列地尔注射液治疗后循环缺血性眩晕效果可靠，能够提高临床疗效，加快后循环血流速度，且不良反应发生率低，值得临床应用。［关键词］丁苯酞；前列地尔注射液；后循环缺血性眩晕；血流速度［中图分类号］R441.2［文献标识码］A［文章编号］1673-721006-0145-04［Abstract］ObjectiveToobservethecurativeefficacyofB

3、utylphthalideincombinationwithAlprostadilInjectioninpatientswithposteriorcirculationischemicvertigo.MethodsOnehundredandtenpatientswithposteriorcirculationischemicvertigowhoreceivedtherapyinHuangshiCentralHospitalofEdongHealthcareGroupfromJanuarytoOctober2016werecollectedasobservationalobjects

4、andrandomlydividedintothecontrolgroupandtheobservationgroupaccordingtorandomnumbertable.Besidesconventionaltreatment，thecontrolgroupwastreatedwithAlprostadilInjection，whiletheobservationgroupwastreatedwithButylphthalideincombinationwithAlprostadilInjection.Aftertreatmentof2weeks，thecurativeeff

5、icacy，bloodvelocityofposteriorcirculationbeforeandaftertreatmentandadversereactionswerecompared.ResultsAssessmentofcurativeefficacyofvertigoshowedthatthetotaleffectiverateintheobservationgroupwasstatisticallyhigherthanthatinthecontrolgroup.Beforetreatment，therewerenosignificantdifferencesofblo

6、odvelocityofbasilarartery，leftvertebralarteryandrightvertebralarterybetweenthetwogroups.Aftertreatment，theindexesaboveinthetwogroupswereallsignificantlyfasterthanthosebeforetreatment，andbloodvelocityofbasilarartery,leftvertebralarteryandrightvertebralarteryintheobservationgroupwashigherthantho

7、seofcontrolgroup.Duringthetreatment，therewasnocasewithsevereadversereactions，andtheincidenceofadversereactionsinthecontrolgroupandtheobservationgrouphadnostatisticallysignificantdifference.ConclusionButylphthalideincombinationwithAlpros