新鲜芦荟外敷联合依托考昔治疗急性痛风性关节炎临床观察

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1、新鲜芦荟外敷联合依托考昔治疗急性痛风性关节炎临床观察【摘要】目的：观察新鲜芦荟外敷联合依托考昔在急性痛风性关节炎治疗屮的临床疗效。方法：将63例急性痛风性关节炎患者随机分为治疗组33例和对照组30例。对照组服用依托考昔治疗，治疗组在对照组治疗的基础上加用新鲜芦荟局部外敷。观察2组治疗前及治疗4h、48h及5d后肿痛评分、实验室指标改善情况及临床疗效，并对不良反应进行评价。结果：治疗组临床痊愈8例，显效18例，有效5例，无效2例，总有效率为93.94%;对照组临床痊愈6例，显效17例，有效4例，无效3例，总有效率为90.00%。2

2、组比较，差异无统计学意义（x2=0.334,P=0.563>0.05）。用药后4h、48h,治疗组肿痛评分与对照组比较，差异冇统计学意义（P0.05）。2组血尿酸、红细胞沉降率、C-反成蛋白水平较治疗前低，差异有统计学意义（P0.05）。结论：新鲜芦荟外敷联合依托考昔短期镇痛起效快，安全有效。【关键词】痛风性关节炎；急性；新鲜芦荟；依托考昔doi：10.3969/j.issn.2095-4174.2016.02.001ClinicalObservationontheTreatmentofAcuteGoutArthritisbyt

3、heCombinationofFreshAloeExternalApplicationandEtoricoxibFANJin-hui，MAHu-sheng，PEIYa~nan,CUIJing-hong[ABSTRACT]Objective：ToobservetheclinicalefficacyoffreshaloeexternalapplicationcombinedwithEtoricoxibinthetreatmentofacutegoutyarthritis.Methods：63casesofacutegoutarthr

4、itiswererandomlydividedintoatreatmentgroup(33cases)andacontrolgroup(30cases).ThecontrolgroupwasgivenEtoricoxib,whilethetreatmentgroupwastreatedbylocalapplicationoffreshaloebasedontheformertreatment.Swellingandpainscoreandlaboratoryindicatorsthetwogroupswereobservedbe

5、foretreatmentand4hours,48hoursand5daysaftertreatment,evaluatingtheadversereactions.Results：Inthetreatmentgroup,8caseswerecured,18casesweremarkedlyeffective,5caseswereeffectiveand2caseswereineffective,thetotaleffectiveratebeing93.94%；whileinthecontrolgroup,6caseswerec

6、ured,17casesweremarkedlyeffective,and3caseswereineffective,thetotaleffectiveratebeing90%.Thedifferencebetweenthe2groupswasnotstatisticallysignificant(x2=0.334,P=0.563>0.05).After4and48hours'medication，thedifferenceofswellingandpainscorebetweenthetwogroupswasstatistic

7、allysignificant(P0.05).Theblooduricacid，erythrocytesedimentationrateandC-reactiveproteinlevelofthetwogroupswerelowerthanthosebeforetreatment,andthedifferencewasstatisticallysignificant(P0.05).Conclusion：FreshaloecombinedwithEtoricoxibissafeandeffectiveforshort-terman

8、algesia.［Keywords］goutarthritis；acute；freshaloe；Etoricoxib急性痛风性关节炎有发病急、疼痛剧烈、常在夜间发病等特点，寻找准确快速的治疗方案，提高临床疗效及患者依从性是临床医生亟待解决的问题，一旦确诊后应快速