《泌尿生殖道感染》ppt课件

《《泌尿生殖道感染》ppt课件》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。

1、InfectionoftheGenitourinaryTractHongshuMaDepartmentofUrologyTianjinFirstCentralHospitalUrinarytractinfections(UTIs)causedbypathogenicbacteriacaninvolveanyofthegenitalorurinaryorgansandeventuallycanspreadfromonesitetoanyoralloftheothers.Definitions1Urinarytractinfec

2、tionisaninflammatoryresponseoftheurotheliumtobacterialinvasionthatisusuallyassociatedwithbacteriuriaandpyuria.MostUTIsarecausedbyaerobicgram-negativerods,(Escherichiacoli.),gram-positivecocci(enterococci)andtoalesserextentbyanaerobicbacteria.Definitions2Definitions3Ba

3、cteriuriaisthepresenceofbacteriaintheurine,whichisnormallyfreeofbacteria,andimpliesthatthesebacteriaarefromtheurinarytractandarenotcontaminantsfromtheskin,vagina,orprepuce.Definitions4PyuriaisthepresenceofwhitebloodcellsintheurineBacteriuriawithoutpyuriaindicatesbac

4、terialcolonizationratherthaninfection.Pyuriawithoutbacteriuriawarrantsevaluationfortuberculosis,stone,orcancer.ClassificationAccordingtotheirnaturehistoryFirstinfections/IsolatedInfectionRecurrentinfectionsBacterialpersistenceReinfectionsReinfectionisrecurrentinf

5、ectionwithdifferentbacteriafromoutsidetheurinarytract.Eachinfectionisanewevent;theurinemustshownogrowthaftertheprecedinginfection.Bacterialpersistencereferstoarecurrenturinarytractinfectioncausedbythesamebacteriafromafocuswithintheurinarytract,suchasaninfectionstoneo

6、rtheprostate.AccordingtoTheirSiteofOriginUpperurinarytractinfectionLowerurinarytractinfectionGenitalsysteminfectionUpper-tractinfectionAcutepyelonephritisChronicpyelonephritisEmphysematouspyelonephritisRenalabscessPerinephricabscessXanthogranulomatouspyelonephritisLow

7、er-tractinfectionAcuteurethralsyndrome(Women)AcutecystitisGenitalinfectionAcuteandchronicbacterialprostatitis.Acuteandchronicepididymitis.PathogenesisBacterialpathogenesisintheurinarytractdependsonanumberoffacters,chiefofwhicharetheBacterialVirulenceFactersandtheHostS

8、usceptibilityFactorBacterialvirulencefactorsAbilityofadherencetourothelialcellsAbilitytoresistbactericidalactivityAbilitytop