异维a酸胶丸联合清肝祛痤方治疗囊肿聚合性痤疮的临床观察

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1、异维A酸胶丸联合清肝祛痤方治疗囊肿聚合性痤疮的临床观察朱黎明（河南省洛阳市机车医院中西医结合科，河南洛阳，471002）[摘要]目的：观察和研究异维A酸胶丸（泰尔丝）联合清肝祛痤方治疗囊肿聚合性痤疮的临床疗效。方法：50例囊肿聚合性痤疮患者随机分为两组，均给予异维A酸胶丸（泰尔丝）每次20mg，每天2次口服。治疗组（n=30）在此基础上加用清肝祛痤方，每日1剂，早晚分服，于治疗初始和2、4、8周时观察评价皮损改善，不良反应及16周时的复发情况。结果：治疗组有效率90.0%，对照组有效率45.0%。治疗组总皮损均数、炎症性皮损均数、非炎症性皮损均数治疗8周后与治疗前比较，差异有统

2、计学意义（p＜0.05或p＜0.01）。对照组总皮损均数、炎症性皮损均数治疗8周后与治疗前比较，差异有统计学意义（p＜0.05或p＜0.01），非炎症性皮损均数治疗8周后与治疗前比较，差异无统计学意义（p＞0.05）。治疗组治疗8周后总皮损均数、非炎症性皮损均数与对照组相比较，差异有统计学意义（p＜0.05或p＜0.01），炎症性皮损均数治疗后两组比较差异无显著性（p＞0.05）。结论：异维A酸胶丸（异维A酸胶丸）联合清肝祛痤方治疗囊肿聚合性痤疮疗效肯定，复发率低且不良反应少。关键词：异维A酸胶丸；清肝祛痤方；囊肿聚合性痤疮；皮损TreatmentofCystJialingRi

3、verAcnewithIsotretinoinSoftCapsuleCombinedwithQing-ganQu-cuoRecipe.英文题目意思与中文题目意思不相符ZhuLiming,DepartmentofIntegratedTraditionalandWestenMedicine,HenanProvinceLuoyangCityLocomotiveHospital,Henan(471002).ABSTRACTObjective:ToobserveandstudyIsotretinoinsoftcapsules(TaiErSi)combinedwithQing-ganQu-

4、cuorecipeintreatingcystjialingriveracne.Methods:50patientscystjialingriveracnepatientswererandomlydividedintotwogroups,Isotretinoinsoftcapsules(TaiErSi)20mg,2timeseveryday.Thetreatmentgroup(n=30)wasaddedwithqing-ganqu-cuorecipedaily.Inthetreatmentofinitialand2,4,8weeks,observingandstudyingth

5、elesions’recovery,assessingskinevaluationfor16weeksandadversereactionofrecurrence.Results:Theefficiencyoftreatmentgroupandcontrolgroupwas90.0%vs45.0%.Totalskinlesionsmeans,inflammatorylesionsmeansandnoninflammatorylesionsmeansoftreatmentgroup8weeksaftertreatmentwithbeforetreatment,werestatis

6、ticallysignificantdifference(p<0.05orp<0.01).Thecontrolgroup’stotalskinlesionsmeansandinflammatoryskinlesionsmeansof8weeksaftertreatmentcomparedwithbeforetreatmentwerestatisticallysignificantdifferente(p<0.05orp<0.01),thenoninflammatorylesionsmeansofcontrolgroupbeforeandaftertreatmentwerenos

7、ignificantdifferente（p＞0.05）.8weeksaftertreatment,totalskinlesionsmeansandnoninflammatoryskinlesionsmeansoftreatmentgrouparebetterthanthoseofcontrolgroupsignificantly(p<0.05orp<0.01),theinflammatorylesionsmeansofbothgroups8weeksaftertreatmentwereno