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1、不同类型的降压药物对高血压患者脉搏波速度的影响分析论文.freelmHgvs(20.7±5.3)mmHg、(19.6±6.1)mmHg、(21.5±4.3mmHg)和舒张压下降幅度(△DBP)(20.8±7.1)mmHgvs(13.97±7.6)mmHg、(14.1±6.8)mmHg、(14.9±4.2)mmHg明显高于其他三种药物(P0.05)。结论常用降压药物可以降低高血压患者的脉搏波速度,改善动脉顺应性。【关键词】高血压;脉搏波速度;苯磺酸左旋氨氯地平;培多普利;琥珀酸美托洛尔缓释片【Abstract
2、】ObjectiveToevaluatetheeffectsofvariousantihypertensivedrugtreatmentonBrachial-anklepulselydividedintofourgrouptreatedvariousantihypentivedrug.GroupA30cases(levamlodipinebesylate2.5mgoncedaily),groupB30cases(perindopril4mgoncedaily),groupC30cases(metoprolo
3、lsuccinatesustained-releasetablets47.5mgoncedaily),groupD30cases(valsartan80mgoncedaily)fortalbloodpressureasthecontrolgroup.Thelevelsofserumbloodlipidandbloodglucose,.freeleasuredrespectivelyinpatientsalbloodpressure.Aftertentrespectively,theSDP,DBPandbaP
4、etoprololsuccinatesustained-releasetablets高血压是动脉硬化最常见的危险因素之一,也是引起脑卒中、心力衰竭、冠心病、肾功能不全的主要原因1-3,臂-踝脉搏波速度(brachio-anklepulsechannelblocker,CCB)、血管紧张素转换酶抑制剂(angiotension-convertingenzymeinhibitors,ACEI)、β-受体阻滞剂和血管紧张素受体拮抗剂(angiotensinreceptorblocker,ARB)是临床常用的降压药
5、物,本研究旨在观察上述四类常用降压药物对既往未经治疗的初诊高血压患者P,etal.Increasedbrachial-anklepulseicsmallvesseldiseaseinelderlyhypertensivepatients.ClinNeurolNeurosurg,2008,110(60):599-604.9NakanoT,OhkumaH,SuzukiS.AssessmentofvascularinjuryinpatientseasurementofpulseprosaM,HaffnerS,et
6、al.Effectofprogressionfromimpairedglucosetolerancetodiabetesoncardiovascularriskfactorsanditsameliorationbylifestyleandmetforminintervention:theDiabetesPreventionProgramrandomizedtrialbytheDiabetesPreventionProgramResearchGroup.DiabetesCare,2009,32(4):726-
7、732.10NamJS,ParkJS,ChoMH,etal.Theassociationbetetabolicsyndromeandadiponectininpatientspairedfastingglucose:cardiovascularrisksandadiponectininIFG.DiabetesResClinPract,2009,84(2):145-5.11KimSG,RyuOH,KimHY,etal.Effectofrosiglitazoneonplasmaadiponectinlevels
8、andarterialstiffnessinsubjectsetabolicsyndrome.EurJEndocrinol,2006,154(3):433-440.12OnoY,NakayaY,BandoS,etal.Telmisartandecreasesplasmalevelsofasymmetricaldimethyl-L-arginineandimproveslipidandglucosemetaboli
