血脂水平与冠状动脉内支架术后再狭窄的关系

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1、2008届临床七年制硕士研究生毕业论文Therelationshipbetweenserum-cholesterolandintracoronaryin-stentrestenosisABSTRACTTheBackgroundandpurpose:Gruentzigcarriedonthefirstcaseofthepercutaneoustransluminalcoronaryangioplasty(PTCA)in1977Hereafterinmorethan20yearspercutaneouscoronaryintervention(PCI)hasgott

2、enrapiddevelopmentInthedevelopmentofPCIthecriticalproblemwearefacingisthehighrateofrestenosishappening6monthsafteroperation,whichisabout30-50%SoourmainconcernisnowonthepathophysiologicalmechanismofthiscourseToevaluatetherelationshipbetweenserum-cholesterolandintracoronaryin-stentrest

3、enosisduringangiographicfollow-upwestudyandresearchtheaffectivefactorthough370caseswhohaveacceptedthesecondcoronaryarteryangiographyinourhospitalfrom2001-52006-10bythemethodofQCA42008届临床七年制硕士研究生毕业论文Methods:370patientswhowereimplantedstentincoronaryarteryandreangiographiedinourhospita

4、lfrom2001-52006-10wereselectedinourinvestigationTherewere94caseswithin-stentrestenosisand276caseswithoutin-stentrestenosisAllcasesweredividedintotwogroupsaccordingtotheresultofangiographyiftherewasrestenosisThedefinitionofrestenosisiswithin5mmoutsidefromthestent.Thereferencevesslesar

5、ethenormalbloodvesselfarsidethelesionTheradiographymachineisVOCdigitalsubtractionangiography(DSA)fromGEcompanyinAmericanTheoperationmethodwasthemethodofJudkin’spuncturethroughrightfemoralarteryThediseasedvesselswerephotographedbyleftanteriorobliqueandcranial,post-anteriorandcaudallef

6、tandlateral,rightandlateralposition.Accordingtodividingthecaseintorestenosisgroup(n=94)andwithoutrestenosisgroup(n=276)thencompareddangerousfactors,characteristicoflesionsoftwogroupsanalysedthedatawithsoftwareofSAS612Thedataofnumericalvariablewereanalysedwitht-testthedataofcategorica

7、lvariablewereanalysedwithx2testP<005hassignificantdifferencesforstatisticsResults:uIn370patients487coronarystentswereimplanted.In-stentrestenosis52008届临床七年制硕士研究生毕业论文wasoccurredin123lesionsof94patientsRestenosisrateis25.4uTherewassignificantdifferenceinhighlow-densitylipoproteinlowhig

8、h-densitylip