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1、Sovaldi(sofosbuvir)使用说明书批准日期：2013年12月6日；公司：GileadSciencesSovaldi是第一个无需与干扰素的共同给药的药物已被证实安全和有效治疗某些类型HCV感染。 SOVALDI完整处方资料。SOVALDITM(sofosbuvir)片，为口服使用 美国初次批准：2013 适应证和用途SOVALDI是一种丙型肝炎病毒(HCV)核苷酸类似物NS5B聚合酶抑制剂适用为慢性丙型肝炎(CHC)感染的治疗作为组合抗病毒治疗方案的一个组分。(1) （1）SOVALDI疗效
2、已在有HCV基因型1，2，3或4感染受试者中被确定，包括有肝细胞癌符合米兰[Milan]标准(等待肝移植)和有HCV/HIV-1共-感染受试者。(1) 剂量和给药方法（1）一片400mg片每天1次有或无食物服用。(2.1) （2）应与利巴韦林[ribavirin]联用或与聚乙二醇化干扰素[pegylated干扰素]和利巴韦林联用为CHC的治疗。建议联合治疗：(2.1) accidentoccurred,thedirectpunishment0.5-10,000yuan,responsibleforthe
3、directresponsibilityfortheaccidentandtheresponsibilityofleadership,suchasconcerningadministrativesanctionsshouldbedealtwithbythepersonnelDepartmentofthecompany.(3)personalinjuryaccidentoccurs,thedirectpunishment500-1000,whoisdirectlyresponsiblefortheacci
4、dentresponsibility,givenoticeofcriticismand50-100economicsanctionsagainstthem.(4)toconcealtheaccident,reportedwithoutunduedelayorfalse,toinformtheadministrativeleadershipofthecriticism,resultinginseriousconsequences,thepursuitofleadership,alongwith500-10
5、00punishment.(5)significantnearmissshouldbeattemptedasthecaseofresponsiblefortheaccidentandconstructionteaminjuriesaccidentpenaltyprovisions,mutatismutandis.Eight,shouldperformintheconstructionstandardsandspecifications,serialnumbera1GB3323-2005steelfusi
6、onweldedbuttjoints,weldingengineering-Raylightingandqualityratingof2GB11345-89steelweldsmanualmethodsofultrasonicinspectionandtestingresultsforgrade3GB50236-2002industrialpipeweldingengineeringcodeforconstructionandacceptanceoffieldequipment4HGJ222-92tec
7、hnicalspecificationforweldingofaluminiumanditsalloys5lowtemperaturesteelweldingprocedure6SH3525-2004petrochemicalJB/T4708-2000ofweldingprocedurequalificationforsteelpressurevessels7JB/4709-20008JB4730-2005pressurevesselweldingproceduresofsteelpressureves
8、selNDT9JB/T4744-2000steelpressurevesselproductsmechanicalpropertiestestofweldedplateII,mechanicalequipmentinstallationengineering1GB150-982GB50128-2005verticalcylindricalsteelpressurevesselsteelweldedspecificationforconstr
