mri常规平扫及dwi检查在甲状腺良、恶性结节鉴别诊断价值中的研究

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1、授予单位代码10089学号或申请号20153302中国图书分类号R445.2HebeiMedicalUniversity硕士学位论文专业学位MRI常规平扫及DWI检查在甲状腺良、恶性结节鉴别诊断价值中的研究研究生：刘娅萍导师：朱青峰副教授专业：影像医学与核医学二级学院：河北医科大学第二医院2018年3月目录中文摘要···········································································1英文摘要···············································

2、····························2英文缩写···········································································4综述MRI常规平扫及DWI检查在甲状腺良、恶性结节鉴别诊断价值中的研究··········································································5致谢································································

3、···············21个人简历·······································································22中文摘要MRI常规平扫及DWI检查在甲状腺良、恶性结节鉴别诊断价值中的研究摘要甲状腺结节是甲状腺常见疾病，随着甲状腺结节发病率的增高，甲状腺手术患者也越来越多。良、恶性甲状腺结节的临床处理不同，对于患者生存质量的影响和涉及的医疗花费有显著差异[1]，术前定性诊断具有重要意义。此外，尽管国内外已有相关指南对治疗甲状腺作出指导和规范，但实际工作中甲状腺治疗不足与治疗过度仍时有发生。故

4、良、恶性甲状腺结节的鉴别是甲状腺结节的评估要点及难点。超声检查费用低、便捷无创、软组织分辨率高，是目前甲状腺病变应用最广泛的影像检查，但除了海绵状结构、囊性结节诊断甲状腺良性结节的准确性高，基本排除恶性外，其它超声征象不能单独诊断及排除恶性[2]；穿刺病理总的准确率较高，但存在假阴性率及假阳性率；CT检查因放射性及碘造影剂的应用而使用受限；核素显像对结节良、恶性的鉴别价值有限。探讨新检查技术有望弥补其它检查局限性，为临床提供更多有价值的诊断信息。MRI检查无创无辐射、视野广、多参数成像、有良好的软组织对比及空间分辨率，且功能成像前景广阔。弥散加权成像（diffus

5、ionweightedimaging，DWI）是功能成像技术，从细胞和分子水平研究疾病的病理生理状态。通过总结MRI平扫及DWI检查下病变的影像学征象，探讨其在甲状腺良恶性结节鉴别诊断中的价值。关键词：甲状腺结节，超声，CT，MRI，弥散加权成像1英文摘要Thediagnosticvalueofdiffusionweightedimaging(DWI)andMRIplainscanindifferentialdiagnosisofbenignandmalignantthyroidnodulesABSTRACTThyroidnodulesarecommonthyro

6、iddiseases,andastheincidenceofthyroidnodulesisincreasing,moreandmorepatientshaveundergonethyroidectomy.Thetreatmentofbenignandmalignantthyroidnodulesisverydifferent,andtherearesignificantdifferencesinThequalityofthepatient'ssurvivalandthemedicaicostsinvolved,thereforethepreoperativequ

7、alitativediagnosisisofgreatsignificiance.Althoughtherelatedguidelinesforthyroidtreatmentareusedasguidelinesandstandardsathomeandabroad,thereisstillainadequateorovertreatmentinthyroidlesions.Therefore,theidentificationofbenignandmalignantthyroidnodulesisanimportantpointanddifficultyine

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