血清shla―g动态变化在先兆流产结局中的研究

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1、血清sHLA-G动态变化在先兆流产结局中的研究摘要：H的：通过定量测定正常妊娠者、先兆流产继续妊娠者及流产者体内血清sHLA-G水平，探讨其动态变化与妊娠结局的关系。方法:选取2015年7月至12月就诊于长沙市妇幼保健院并要求保胎的先兆流产患者根据保胎结局分为继续妊娠组和流产组，同期在我院定期常规产检的正常妊娠孕妇为对照组，采用ELISA法于妊娠第5-10周每周一次定量检测50例正常妊娠孕妇及140例先兆流产并要求保胎治疗孕妇体内血清sHLA-G变化值。结果：随着孕周的进展，三组血清sHLA-G均呈下降趋势，但流产组血清sHLA-G基础值偏低，且下降速度较快，

2、对照组、继续妊娠组及流产组血清sllLA-G在孕5周时分别为(84.32±7.02)U/ml、(82.36±6.65)U/ml、(52.77±5.23)U/ral,到孕10周吋则分别下降为(60.47±5.31)U/ml、(58.71土5.02)U/ml、(9.73±2.82)U/ml,同一孕周水平，三组之间的sHLA-G水平差异均有统计学意义(P<0.05)；对照组与继续妊娠组患者体内血清sHLA-G水平差异无统计学意义(P〉0.05),流产组与继续妊娠组患者体内血清sIILA-G水平差异显著。结论：sHLA-G基础值偏低及降低速度过快可能会导致原因不明性流

3、产的发生。本文采集自网络，本站发布的论文均是优质论文，供学习和研宄使用，文中立场与本网站无关，版权和著作权归原作者所有，如有不愿意被转载的情况，请通知我们删除己转载的信息，如果需要分享，请保留本段说明。关键词：先兆流产；sIILA-G；结局预测中图分类号：R714文献标识码：A文章编号：1671-2064(2017)12-0188-03Abstract:Objective:ToinvestigatetherelationshipbetweenscrumlevelsofsHLA~GanditsAccordingtotheoutcomeofpregnancy,th

4、epatientsweredividedintotwogroupsdynamicchangesandpregnancyoutcomthroughquantitativedetermination.Methods：patientswiththreatenedabortionandtocolytictreatmentinchangshamaternalandchildhealthcarehospitalfromjuly2015todcccmbcrasPregnancygroupandabortiongroupaccordingtopregnancyoutcome,

5、normalpregnantwomenascontrolgroup.QuantitativedetectedtheserumsHLA-Gof50casesofnormalpregnantwomenand140casesofthreatenedabortionthataskedtocolytictherapybyenzymelinkedimmunosorbentassay(ELISA).Results：Withthedevelopmentofgestationalweeks,theserumsllLA-Glevelsofthethreegroupsshoweda

6、downwardtrend,buttheserumsHLA~Gvaluewaslowerinabortiongroup,andtherateofdeclinewasfaster.At5weeksofgestation,TheControlgroup,pregnancygroupandabortiongroupserumsHLA-Gwere(84.32+7.02)U/ml，(82.36+6.65)U/ml(52.77+5.23)respectively，whenlOweeksofgestation,theydecreasedto(60.47±5.31)U/ml、

7、(58.71±5.02)U/ml、(9.73±2.82)U/mlrespectively.ThelevelsofsllLA-Gwerestatisticallysignificantatthesamegestationalweekbetweenthethreegroups(P<0.05)，therewasnosignificantdifferenceinserumsHLA-Gbetweenthecontrolgroupandthepatientswiththreatenedabortion(P>0.05),itisoppositebetweenabortion

8、groupandcontinuedpr