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时间:2018-10-28
《微波灭活髓内钉固定治疗长骨骨干转移瘤的疗效观察》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、微波灭活髓内钉固定治疗长骨骨干转移瘤的疗效观察賴阮之平am腿麵西安交通大学第一附属医院骨科西安交通大学第附属医院肿瘤内科摘要:目的探讨微波原位灭活病灶刮除骨水泥填充加交锁髓内钉固定的方法治疗长骨骨干转移瘤的疗效。方法收集2009-012014-06丙安交通大学第一附属医院收治的四肢长骨骨干转移瘤23例(23处),均采用微波原位火活、病灶刮除、骨水泥填充加交锁髓内钉固定的方法治疗,其屮20例伴有病理性骨折。术前术后分别采用视觉模拟评分(VAS)评价疼痛程度,Enncking评分评价肢体功能,Karnofsky评分评价
2、生活质量。结果全部病例均获随访,时间4-24个月,平均16.2个月。手术顺利,无术中死亡病例,术后切口均一期愈合。局部复发1例,无感染病例。无骨水泥及髓内钉松动、断裂等情况发生。随访期间死亡14例,存活9例,总体半年生存率91.3%,1年生存率69.6%,2年生存率39.1%。术后视觉模拟评分、Enncking评分、Karnofsky评分较术前均有改善。结论采用瘤段微波原位灭活、病灶刮除、骨水泥填充加交锁髓内钉W定的方法治疗长骨骨干转移瘤,可以恢复患者的完全负重能力,减轻疼痛,提高生存质量,是一种有效的外科治疗方法
3、。关键词:骨转移瘤;微波;髓内钉;外科治疗;作者简介:李嘉,男,1989-12生,博士,住院医师,助理研究员,E-mail:happylee-xjtu@163.com作者简介:李萌,E-mail:drleemon@163.com收稿日期:2017-08-10基金:国家临床重点专科建设资助项目TheefficiencyofinsitumicrowaveablationcombinedwithintramedullaryinterlockingnailonlimbdiaphysealmetastasesLIJiaJIW
4、enchenRUANZhipingHANXuezheYANGYiminDAIXingLIMengDepartmentofOrthopedics,FirstAffiliatedHospitalofXi'anJiaotongUniversity;DepartmentofMedicalOncology,FirstAffiliatedHospitalofXi'anJiaotongUniversity;Abstract:ObjectiveToevaluatetheefficiencyofinsitumicrowaveabla
5、tion,clearanceoffocallesion,cementinfillingcombinedwithintramedullaryinterlockingnailonlimbdiaphysealmetastases.MethodsTwenty-threepatientswithlimbdiaphysealmetastasesweretreatedwithinsitumicrowaveablation,clearanceoffocallesion,cementinfillingcombinedwithintr
6、amedullaryinterlockingnailfromJanuary2009toJune2014intheFirstAffiliatedHospitalofXi’anJiaotongUniversity.Of23patients,20patientswereaccompaniedbypathologicalfractures.Thevisualanaloguescale(VAS)scorebeforeoperationand3monthsafteroperationwereinvestigated.Inadd
7、ition,EnnckingscoreanclKarnofskyperformancescalewereassessed.ResultsAllofthe23patientswerefollowedupfor4-24monthswiththeaveragefollow-upperiodof16.2months.Alltheoperationsweresuccessfulwithoutpatientdeathduringtheoperationandallincisionsachievedprimaryhealing.
8、Onecaseoflocalrecurrencewasobservedandtherewerenocomplicationsincludinginfection,looseningorbreakageofinternalfixation.Duringthefollow-upperiod,14patientsdied.Thepostoperative6-mon
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