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1、新生儿ABO溶血病的早期诊断及治疗分析刘明喜1葛艳2(1新疆沙雅县人民医院儿科新疆阿克苏843200)(2阿克苏市人民医院儿科新疆阿克苏843200)【摘要】目的:对新生儿ABO溶血病的早期诊断及治疗进行分析。方法:选择2013年4月〜2015年4月到我院儿科进行治疗的新生儿ABO溶血病患儿96例,根据出生后是否进行早期溶血试验检查,将其分为观察组和对照组,各48例。对两组患儿胆红素峰值、光疗时间、住院时间等指标间的差异进行对比分析。结果:观察组和对照组应用静脉丙种球蛋白分别在生后48h内和生后48h后。观察组肭红素峰值、光疗时间和平均住院时间分别为219.45&p
2、lusmn;15.37,68.52±7.64h和6.85±0.81d;对照组分别为298.76±18.39μmol/L、87.45±8.71h和8.53±1.26d,差异均有统计学意义(P<0.05)。结论:新生儿ABO溶血病高危患儿在生后进行溶血试验检查可以及时确诊新生儿ABO溶血病,且在患儿出生48h内应用静脉丙种球蛋白可以有效控制患儿胆红素水平,缩短光疗时间和病程,值得临床推广应用。【关键词】新生儿;ABO溶血病;早期诊断;治疗【中图分类号】R722【文献标识码】A【文章编号】2
3、095-1752(2016)10-0032-02AnalysisofearlydiagnosisandtreatmentofneonatalABOhemolyticdiseaseLiuMingxi.ThePeople’sHospitalofShayaCounty,Xinjiang,Akesu843200,China,GeYan.ThePeople’sHospitalofAkesuCity,Xinjiang,Akesu843200,China[Abstract]ObjectiveToanalyzetheearlydiagnosisandtreatmentofABOhe
4、molyticdiseaseofthenewborn.Methods96patientswithABOhemolyticdiseaseofnewborninfantstreatedbyourhospitalfromApril2013toApril2015weredividedintoobservationgroupandcontrolgroupwith48casesineachgroup.Thecomparativeanalysisofthedifferencesbetweenthetwogroups,thepeakbilirubinphototherapytime
5、,hospitalizationtimeandotherindicatorsbetween.ResultsTheobservationgroupandthecontrolgroupwithintravenousimmunoglobulinrespectivelyin48hafterbirthandafterbirthafter48h.Observationgroup,bilirubinpeak,phototherapytimeandtheaveragetimeofhospitalizationwere219.45±15.37and68.52+7.64h
6、and6.85±0.81d;controlgroup298.76±18.39mol/L,87.45±didand8.53±1.26D,thedifferenceswerestatisticallysignificant(P<0.05),respectively.ConclusionABOhemolyticdiseaseofnewbornchildrenwithhigh-riskafterbirthofhemolysistestcanbetimelydiagnosisofABOhemolyticdiseas
7、eofthenewborn,andinchildrenbornwithin48hoursafterapplicationofintravenousimmunoglobulin(IVIG)caneffectivelycontrolthelevelofserumbilirubin,shortenthetimeanddurationofphototherapy,worthyofclinicalapplication.【Keywords】Newborn;ABOhemolyticdisease;Earlydiagnosis;Treatment新生儿ABO溶血病在临床上比较