敷脐疗法治疗心脾两虚失眠临床疗效及对褪黑素影响的研究

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1、学位论文敷脐疗法治疗心脾两虚失眠临床疗效及对褪黑素影响的研究中文摘要目的：通过观察敷脐疗法治疗心脾两虚失眠的临床疗效及对褪黑素的影响，为临床脐疗法治疗失眠提供参考依据，并对其原理进行初步探讨。方法：将66名患者随机分成治疗组和对照组。治疗组采用补益气血中药敷脐治疗，隔日治疗1次；对照组使用安慰剂隔日1次敷脐治疗，10天为一个疗程。连续治疗3个疗程后使用中医证候、失眠程度、匹兹堡睡眠质量指数及血清褪黑素含量变化等指标进行治疗前、后的组内及组间的临床疗效评定。结果：66例失眠症患者中63例完成治疗，其中剔除1例，脱落2例，一个月后63例完成随访。连续治疗3个疗程后，治疗组总有效率93.75

2、%，治愈率12.50%；对照组总有效率74.19%，治愈率3.22%。两组间比较，在中医证候评价、失眠程度、匹兹堡评分、血清褪黑素含量变化上有统计学差异（P<0.05）。治疗组自身治疗前、后比较，中医证候评价、患者本人对失眠程度判断、匹兹堡评分、血清褪黑素含量变化有统计学差异（P<0.05）。结论：1.敷脐疗法改善心脾两虚型失眠症临床症状疗效肯定，且疗效与治疗次数呈正相关，疗次越多，疗效越好。2.敷脐疗法在改善心脾两虚型失眠症临床症状的同时可升高血清褪黑素水平，与对照组相比，差异有显著性意义。关键词：心脾两虚型失眠症；临床研究；敷脐疗法；褪黑素1ABSTRACTObjective:To

3、observetheeffectsoftheumbilicustherapyandtheimpactonmelatoninforinsomniaofdeficiencyofbothheartandspleen,andtoprovidereferencebasisfortheumbilicustherapytotreatinsomnia,preliminarilytodiscusstheprincipleofthetreatment.Methods:66patientswererandomlydividedintotreatmentgroupandcontrolgroup.Thepati

4、entsoftreatmentgroupweretreatedwithtonifyingChinesemedicinalcroptoapplyumbilicusonceeveryotherday.Thecontrolgroupwastreatedwithplaceboeveryotherday.Acourseoftreatmentlastedfor10days.Afterthreeconsecutivesessions,theefficacyassessmentwascarriedoutwithSyndromeevaluation,Insomniadegreeevaluation,Pi

5、ttsburghSleepQualityIndexandChangesofserummelatoninlevelsbeforeandafterthetreatment.Results:63casescompletedthefulltreatment.Theoverallefficacyofthetreatmentgroupwas93.75%,andcureratewas12.50%.Thetotaleffectiverateofthecontrolgroupwas74.19%,andcureratewas3.22%.Theefficaciesweresignificantdiffere

6、nces(P<0.05)betweenthetwogroups.Andthereweresignificantdifferences(P<0.05)intreatmentgroup’sowncomparison.Conclusion:1.Theeffectsofumbilicaltherapyfortheclinicalsymptomsofinsomniawereaffirmative.Andtheeffectspositivelycorrelatedtreatmentfrequencies,curetimesmore,thebettertheresults.2.Theumbilica

7、ltherapycouldincreaseserummelatoninlevels,ascomparedwithcontrolgroupsignificance.KeyWords:Insomniaofdeficiencyofbothheartandspleen,Clinicalresearch,Umbilicustherapy,Melatonin2目录引言............................................