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1、孟鲁司特钠在小儿支原体肺炎的作用分析(成都市第六人民医院儿科四川成都610051)【摘要】目的：观察孟兽司特钠联合阿奇霉素对肺炎支原体肺炎儿童临床疗效及肺功能的影响。方法：54例肺炎支原体肺炎患儿随机分为两组，27例采用阿奇霉素治疗，联合治疗组(27例)采用阿奇霉素联合孟魯司特钠治疗，同时选择年龄、性别相匹配的27例健康儿童为对照组。采用肺功能仪测定儿童肺功能指标。结果：阿奇霉素组显效13例，有效10例，无效4例，总有效率为85.2%；联合治疗组显效17例，有效8例，无效2例，总有效率为96.3%,两组比较差异无统计学意义(P>；0.05)o阿
2、奇霉素组治疗后V-T、t-PTEF/t-E%和TEF25/PTEF%分别为10.91±1.45mL/kg、45.43±11.19%、73.15±12.97%,联合治疗组治疗后V-T、t-PTEF/t-E%和TEF25/PTEF%分别为11.22±2.06mL/kg、44.25±17.96%>79.01±10.13%，’冶疗后两组V-T、t-PTEF/t-E%和TEF25/PTEF%较治疗前均有明显改善(P<0.05),尤其以联合治疗组恢复较快，与对照组水平相近
3、(P>；0.05)o结论：孟兽司特钠联合阿奇霉素治疗儿童肺炎支原体肺炎能缩短病程，改善小呼吸道功能。【关键词】孟鲁司特钠；阿奇霉素；肺炎支原体肺炎；潮气量；肺功能检测【中图分类号】R720.5【文献标识码】A【文章编号】1007-8231(2016)24-0114-02TheClinicalSignificanceofMontelukastsodiuminChildrenwithMycoplasmapneumoniaepneumoniFanHuihai.DepartmentofPediatrics,TheSixthPeople'sHospita
4、lofChengdu,SichuanChengdu610051,China【Abstract】ObjectiveToobservetheclinicalcurativeeffect,ofmontelukastsodiumcombinedwithazithromycinonchildrenwithmycoplasmapneumoniaandtheirpulmonaryfunctions.27healthychildrenwhoseageandsexmatchingwereselectedascontrolgroup.Method54childrenw
5、ithmycoplasmapneumoniawererandomlydividedintotwogroups,27casesweretreatedbyazithromycin,thecombinationtherapygroup(27cases)withAzithromycincombinedwithmontelukastsodium.Thechildren’slungfunctionweremensuratedbylungfunctioninstrument.ResultIntheAzithromycingroup,13casesweremark
6、edlyeffective,10caseseffective,4casesinvalid,hetotaleffectiveratewas85.2%.Inthecombinedtreatmentgroup,17casesweremarkedlyeffective,7caseseffective,2casesinvalid,thetotaleffectiveratewas96.3%.Therenosignificantdifferencesbetweenthetwogroups(P>0.05).TheV-T,t-PTEF/t-E%andTEF25
7、/PTEF%ofAzithromycingroupaftertreatmentwererespectively10.91±1.45mL/kg,45.43±11.19%73.15±12.97%,TheV-T,t-PTEF/t-E%andTEF25/PTEF%ofcombinedtreatmentgroupaftertreatmentwererespectively11.22±2.06mL/kg,44.25±17.96%,79.01±10.13%.TheV-T,t-PT
8、EF/t-E%andTEF25/PTEF%inthetwogroupsaftertreatmentwereevidentl
