【高血压精品英文课件】hypertension & cardiovascular risk factors

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1、Hypertension&CardiovascularRiskFactorsFinalYearCardiologyTeaching2003-4OutlineGlobalburdenofcardiovasculardiseaseEpidemiologyofcardiovasculardiseaseHypertensionEpidemiologyClinicalfeaturesInvestigationCardiovascularriskassessmentTheGlobalBurdenofDiseaseThescopeofth

2、eproblemLeadingCausesofDeathandDisability(DALY’s)RankCause%RankCause%1Lowerrespiratoryinfections8.21Ischemicheartdisease5.92Diarrhoealdiseases7.22Majordepression5.73Perinatalconditions6.73Roadtrafficaccidents5.14Majordepression3.74Cerebrovasculardisease4.45Ischemic

3、heartdisease3.45COPD4.26Cerebrovasculardisease2.86Lowerrespiratoryinfections3.17Tuberculosis2.87Tuberculosis3.08Measles2.78War3.09Roadtrafficaccidents2.59Diarrhoealdiseases2.710Congenitalabnormalities2.410HIV2.619902020GlobalBurdenofDiseaseStudy,1996****WorldHealth

4、Report2002MortalityduetoleadingglobalriskfactorsBurdenofdiseaseduetoleadingglobalriskfactors****WorldHealthReport2002CardiovascularriskfactorsBloodpressureLipidsDiabetesSmokingBPandrelativeriskofstrokeandCHDBritMedBull1994;50:272-98ApproximatemeanusualBPApproximate

5、meanusualBP12376123761368413684148911489116298162981751051751054.002.001.000.500.254.002.001.000.500.25StrokeCHDBloodPressureandRiskofCongestiveHeartFailure:theFraminghamStudyAverageannualrate/10,000AgeatexaminationNormotensiveBP<140/90mmHgHypertensiveBP>160/95mmH

6、gKanneletal.1972SystolicBPasariskfactorforrenalfailureSystolicBP,mmHgIncidence/100,000personyearsMRFIT‘screenees’KlagMJ,JAMA‘97;277:1293CholesterolandriskofCHD&cardiovasculardeathApproximatemeanusualcholesterol(mmol/l)4.04.55.05.56.04.002.001.000.500.25RelativeRisk

7、(51652participants,310events)Approximatemeanusualcholesterol(mmol/l)4.04.55.05.56.04.002.001.000.500.25RelativeRiskCoronaryHeartDisease(51652participants,310events)RelativeRiskCardiovascularDeath(9studies,49296participants,938events)Approximatemeanusualcholesterol(

8、mmol/l)4.04.55.05.56.04.002.001.000.500.25Approximatemeanusualcholesterol(mmol/l)4.04.55.05.56.04.002.001.000.500.25EasternStroke&CoronaryHeartDi