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ID:20259095
大小:7.07 MB
页数:65页
时间:2018-10-11
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1、IntroductiontoCardiovascularPathology-FredClaytonSystemicPathologyofCongestiveHeartFailurePathologyofMyocarditisPathologyofCardiomyopathyDilatedCardiomyopathyHypertrophicCardiomyopathyRestrictiveCardiomyopathyCongestiveHeartFailureCardiacoutputinsufficientformetabolicrequirementsofthe
2、bodySystolicdysfunction–decreasedmyocardialcontractilityDiastolicdysfunction–insufficientexpansionforventricularvolumeProblemsareaccentuatedbyincreaseddemand–highoutputheartfailureCHF–Body’sCompensationTachycardiaFrank-Starling–increasedEndDiastolicVolumeMyocardialhypertrophyRenin-angi
3、otensin-aldosteronesystemCatecholamines–positiveinotropiceffectAdrenergicredistributionofbloodflowIncreaseoxygenextractionfromhemoglobinLeft-sidedHeartFailureIschemicheartdiseaseHypertensionAorticandmitralvalvediseaseMyocardialdiseaseLungs–PulmonaryedemaDyspnea–breathlessnessOrthopnea–
4、dyspnealyingdownParoxysmalnocturnaldyspnea–extremedyspneaLung–PulmonaryEdema–palepinkedemafluidfillingalveoliLung–alveolarhemorrhage,heme-filledmacrophages“heartfailurecells”,withironstaintorightKidneys–reducedperfusionIschemictubularnecrosis/ATNPrerenalazotemiaKidney-ATNBraininCHF–cer
5、ebralhypoxiaIrritabilityLossofattentionspanRestlessnessStuporComaRight-sidedheartfailurePurecorpulmonaleConsequenceofleft-sidedfailureMyocardial–myocarditis,cardiomyopathy,constrictivepericarditisRightfailure-systemiceffectsLiver–chronicpassivecongestionSpleen–congestivesplenomegalyKid
6、neys–congestionandhypoxiaSub-Q–peripheraledemaandanasarcaPleuralspace–effusionsBrain–venouscongestionandhypoxiaPortal-ascitesLiver–chronicpassivecongestion–bloodpoolsnearthecentralveinsLiver–chronicpassivecongestionLiver–chronicpassivecongestion–bloodpoolsnearthecentralveinsLiver–chron
7、icpassivecongestion–redcellpoolingnearcentralveinsandpericentralnecrosisofthehepatocytesCHF–finalpathwaytodeathIschemicheartdiseaseHypertensiveheartdiseaseValvularheartdiseaseCardiomyopathyMyocarditisSpecificheartmusclediseasesMyocarditisEtiologyViral–CoxsackieA,ECHO,InfluenzaChlamyd
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