脑卒中与颅内颅外血管疾病的关系及干预对策黄PPT课件.ppt

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1、DistributionofarterialstenosisinacutestrokeandriskfactorsPekingUniversityFirstHospitalDepartmentofNeurologyDr.andProf.HuangYininghuangyn@outmail.net.cnBackgroundThereishighincidenceofintracranialarterialstenosisinChinesestrokepatients.Itisassocatedwithpooroutcomeinthosewitharterialstenosisco

2、mparingwiththosewithoutstenosis.Manyriskfactorsareproved,i.e.age,gender,Hypertension,diabetics.QuestionandPurposeChinaisahugecountry.Therearegreatdifferenceinthegeography,lifestyles,economicdevelopmentfromregionstoregions.Whetherthecerebralarterialstenosisisdependedonregionaldistribution?Whe

3、therthestenosisisdependedoneconomicdevelopment?Standardmanagementofacutestroke10thfiveyearNationalProjectSponsoredbyNationalScientificCommitteeNo：2001BA703B11AmulticenterstudyDataandmethodsInclusioncriteriaFirsttimeofacuteischemicAdmittedinSUanddepartmentofneurologyWithin7daysafteronsetNIHSS

4、≧5InvolvementofanteriororposteriorcirculationContentagreementGroupingforStatisticanalysisWith/withoutarterialstenosisExtracranialgroup/intracranialgroupAnterior/posteriorcirculationAnteriorcirculation:CCA,ICA,TICA,MCA,ACAPosteriorcirculation:SubA,VAe,VA,BA,PCALogisticregression:regions,sizeo

5、fhospitals,age,gender,HTN,DM,LIPIDEnd-pointModifiedRankinScaleindischarge，andfollow-upinmonth3andmonth6goodoutcome:mRS2pooroutcome:mRS>2ResultsandAnalysisDescriptivestatisticsofdata1273casesenrolled106383.5%underwentvascularexaminationAge:61.8±11.0yrsMale:833(65.4%)Followup:1185/1273(93.1%)

6、inmonth31149/1273(90.3%)inmonth6Ratioofarterialinvolvement568(53.4%)caseswitharterialinvolvement:Male:374(65.8%)Female:194(34.2%)StenosisandEconomicDevelopmentClassifythehospitalsas3classes:Class1,thosefromricherregionsClass2,thosefrommoderateregionsClass3,thosefrompoorerregionsThepatientsli

7、vingintherichregionshadhigherincidenceofarterialinvolvementOR=0.856(95%CI,0.751-0.976,p=0.040)StenosisandEconomicDevelopmentpatientsinthehospitalsofclassIisolderthaninclassIIandIIIClassIage=62.55±11.19yrsClassIIage=60.47±12.10yrsClassIIIage=60.72±1