缺血性卒中复发影响因素及他汀类药物对卒中复发的影响

缺血性卒中复发影响因素及他汀类药物对卒中复发的影响

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1、授予单位代码10089学号或申请号20153223中国图书分类号R743.3HebeiMedicalUniversity硕士学位论文专业学位缺血性卒中复发影响因素及他汀类药物对卒中复发的影响研究生:王炳雷导师:王惠娟教授专业:神经病学二级学院:河北医科大学第二医院2018年3月目录中文摘要·········································································································1英文

2、摘要·········································································································2英文缩写·········································································································4研究论文缺血性卒中复发影响因素及他汀类药物对卒中复发的影响前言····

3、·····································································································5材料与方法·····························································································5结果··················································

4、·······················································7附图·········································································································10附表······················································································

5、···················11讨论·········································································································15结论·········································································································21参考文献··········

6、·······················································································21综述缺血性卒中复发影响因素分析·······················································25致谢··························································································

7、·······················36个人简历·········································································································38中文摘要缺血性卒中复发影响因素及他汀类药物对卒中复发的影响摘要目的:研究缺血性卒中患者复发的影响因素,并分析他汀类药物对缺血性卒中复发的影响。方法:连续收集2016年10月份至2017年02月份,于河北医科大学第二医院神经内科住院的脑

8、梗死患者临床资料,并采用电话联系方式对患者出院后用药及恢复情况进行1年的随访,比较他汀类药物依从性好组和依从性差组的复发率情况,并对脑卒中复发进行单因素及多因素分析。结果:1.本研究纳入758例缺血性卒中患者。随访1年,共77例患者复发。3个月内复发率为3.43%,6个月累积复发率为6.72%,1年累积复发率为10.15%。2.缺血性脑卒中复发独立危险因素:性别、糖尿病、冠心病、他汀药物依从性、小动脉闭塞型。3.758例患者出院后,随时间延长,他汀药物依

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