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1、EconomicConsiderationsinthePharmacologicManagementofPain (药物治疗疼痛中的经济因素考虑）LiuZhanXian-JanssenPharmaceuticalLtd.2021/7/2GeneralIntroductionofPain (疼痛概论）Definition(疼痛的定义）Physicalpainisacommon,subjectiveandcomplicatedprocessthatisinitiatedbyanunpleasantsensoryexperience.Itoccursv
2、iaseveralmechanismsthatmayresultinimmobility,deconditioningandemotionalreactions.(躯体疼痛是由于不愉快的感觉经验引起的一种常见的,主观的和复杂的过程.它是通过可引起行动受限,状态异常和情绪反应的一系列机制而发生的.2021/7/2Epidemiology(流行病学资料)>75millionpeopleinU.S.havesomeformofpersistentorrecurrentpain*andpainisthemostcommonsymptomforwhichp
3、atientsseekmedicalassistance**(在美国有超过七千五百万人患有不同程度的持续性或反复发生的疼痛;疼痛已成为患者求医的最常见的症状.在中国,130万癌症死亡人群中,60%以上忍受着中到重度疼痛GeneralIntroductionofPain (疼痛概论）*CaudillM,HolmanG,TurkD.PatientCare.1996:154**FoleyK.CecilTextbookofMedicine.Philadelphia,1992:972021/7/2GreatestChallenge(伟大的挑战)Thegre
4、atesthealthcarechallengeforthenextdecadeistomakethebestuseoflimitedavailableresourcestoattainthehighestqualityofhealthcareforthelowestcost.Aspharmacoeconomicdatabecomeincreasinglyavailable,theiruseincost-effectivepainmanagementandinallhealthcaredecisions,willplayamajorrole.Th
5、epharmacistisuniquelypoisedtoadapttothisshiftingparadigm.*在下一个十年中,对健康领域里的最大的挑战是充分利用可得到的有限资源,利用最低的花费来得到最高的健康质量.由于药物经济学资料的增加,在疼痛控制健康项目决策中,其花费和结果的研究将起主要作用.药剂师们在适应这场变更中起着独一无二的平衡作用.GeneralIntroductionofPain (疼痛概论）*MichaelRigas,EconomicConsiderationsinthePharmacologicManagementofPa
6、in.P&Ts1997:4542021/7/2ClassificationofPain(疼痛的分类)TemporalClassification(时间分类)AcutePainChronicPainusuallydefinedasthatlasting6monthsorlongerthetiming,localizationandcharacterofthepainareoftenmorevague(疼痛的时间,部位和性质经常是含糊的)Theremaybeindicationsofsleepdisturbances,lossofappetite,d
7、ecreasedlibido,weightlossanddepression.(经常伴有睡眠干扰,食欲不振,性欲下降,体重降低及抑郁)PhysiologicClassification(生理学分类)Somatic,Visceral,Neuropathic(躯体,内脏,神经性)GeneralIntroductionofPain (疼痛概论）2021/7/2PainManagementPrinciples(疼痛控制原则)*AcutePainpatienteducationonpostoperativepaintheneedforregularlysc
8、heduledanalgesicsasopposedtoas-neededanalgesicsforthefirst24hoursofm
