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1、AdvancedincervicalcancerscreeningEpidemiologicalstatusofcervicalcancerCervicalcanceristhethirdmostcommonmalignancyamongwomenworldwideEstimatedabout500,000newcasesofcervicalcanceroccuramongwomenworldwideeachyearOfthose,80%occurinthedevelopingcountriesandareas,andahalfinAsiaParkinDM,CAC
2、ancerJClin.2005;55EstimatedNewCancerCasesandDeathsbySex,UnitedStates,2011JemalA,etal.CACancerJClin2011EstimatedNewCancerCasesandDeathsbySex,UnitedStates,2011JemalA,etal.CACancerJClin2011Newcasesofcervicalcancerworldwidein2000(N=466,000)SouthAmerica*:77,000Parkin,2000Asia*235,000Africa
3、*69,00018%50%15%17%Developedcountries85,000*developingcountriesorareasEpidemiologicalstatusofcervicalcancerinChinaCervicalcancerisalsothesecondmostcommonmalignancyinChinaassameasworldwide130,000newcasesofcervicalcancerperyearinChina,accountingfor1/4ofworldwidecasesUnevendistributionof
4、frequencyindifferentareasinChinaHigherfrequentareasaremainlydistributedinthemiddleandwesternareasofChina,suchasGanshu,sichuan,Jiangxi,shanxi,andothersContrarily,relativelowerareasineasternpartsofChina,includingZhejiangProvinceEpidemiologicalstatusofcervicalcancerinChinaEpidemiologyofH
5、PVinfectioninfemalegenitaltrackintheWorldIthasbeenwellknownThelifetimeriskofHPVinfectioninfemalegenitaltractisestimatedtobe75%ormoreQuitehighfrequencyofHR-HPVinfectionhasbeendetectedincervicalcanceranditsprecursors,ofthose,HPV16/18arepredominanttypesTheprevalenceofHPVinfectionisquitev
6、ariedamongdifferentcountriesorareasBasemanJG.JClinVirol2005;32Suppl1:S16HPVTypesinCIN2/3andCervicalCancer02040608010016+18+45+31+X+33+52+58+35+59+5657.6%71.7%77.4%81.3%85.0%87.9%90.1%91.8%93.3%94.6%95.7%ProportionofCancersAssociatedwithHPVtypesMunozN.BoschFX.Etal.InternationalAgencyfo
7、rResearchonCancerMulticenterCervicalCancerStudyGroup.Epidemiologicclassificationofhumanpapillomavirustypesassociatedwithcervicalcancer.EnglandJournalofMedicine.348(6):518-27,2003.NewCervicalCancerScreeningRecommendationsNewCervicalCancerScreeningRecommendationsfromtheU.S.PreventiveSer
8、vices
