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1、[InsertNameofpresenter][InsertNameofhospital]Usingantibioticsprudently-HospitalPrescriberPresentationContentsofthispresentationAntibioticresistance–apatientsafetyissueSituationinIrelandDriversofantibioticresistanceConsequencesofantibioticresistanceWhy
2、inappropriateuseofantibioticscontributestoantibioticresistance–the“why”Howprudentuseofantibioticscanbepromotedinhospitals–the“how”EuropeanAntibioticAwarenessDay–acampaigntopromoteprudentuseofantibiotics2Antibioticresistance–apatientsafetyissue3Antibi
3、oticresistance–aprobleminthepresentandthefutureAntibioticresistanceisanincreasinglyseriouspublichealthproblem:resistantbacteriahavebecomeaneverydayconcerninIrishhospitals.4Trendsinantibioticresistance(invasiveinfections)inIreland,2002-2009.Source:Eur
4、opeanAntimicrobialResistanceSurveillanceSystem(EARSS)andHealthProtectionSurveillanceCentre(HPSC).20022007Meticillin-resistantStaphylococcusaureus(MRSA)bloodstreaminfectionsinEuropeNodata<1%1-5%5-10%10-25%25-50%>50%Source:EuropeanAntimicrobialResistanc
5、eSurveillanceSystem(EARSS),2008.5S.aureus/MRSAbacteraemiatrendsbyquarter,2002-2010Q2**Datafor2010provisionaluptotheendofQ2;Numberoflaboratoriesparticipatingbyyear-endindicatedabovetheQ4barsMRSAinEurope,2007:oftenhigh,butdecreasinginmanycountriesCount
6、rywithasignificantincrease(2005–2007)Countrywithasignificantdecrease(2005–2007)MRSA(%)Source:EARSS&ECDC,2009No.ofcountries7IrelandAntimicrobialresistanceingram-negativebacteria,EU,2007:alreadyhighorincreasingCountrywithasignificantincrease(2005-2007)
7、Countrywithasignificantdecrease(2005-2007)Carbapenem-resistantPseudomonasaeruginosa(%)3rd-gen.ceph.-resistantKlebsiellapneumoniae(%)3rd-gen.ceph.-resistantEscherichiacoli(%)Source:EARSS&ECDC,2009No.ofcountriesNo.ofcountries8Source:EuropeanSurveillanc
8、eofAntimicrobialConsumption(ESAC),2010.In:ECDCAnnualEpidemiologicalReport2010:inpress.TotaloutpatientantibioticuseinEUMemberStates,IcelandandNorway,20089*Totaluse,i.e.includinginpatients(CY,GR,LT).**Reimbursementdata,i.e.notincludingover-the-c