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1、[InsertNameofpresenter][InsertNameofhospital]Usingantibioticsprudently-HospitalPrescriberPresentationContentsofthispresentationAntibioticresistance–apatientsafetyissueSituationinEuropeDriversofantibioticresistanceConsequencesofantibioticresistanceWhyinappropriateuseofantib
2、ioticscontributestoantibioticresistance–the“why”Howprudentuseofantibioticscanbepromotedinhospitals–the“how”EuropeanAntibioticAwarenessDay–acampaigntopromoteprudentuseofantibiotics2Antibioticresistance–apatientsafetyissue3Antibioticresistance–aprobleminthepresentandthefut
3、ureAntibioticresistanceisanincreasinglyseriouspublichealthproblem:resistantbacteriahavebecomeaneverydayconcerninhospitalsacrossEurope.4Trendsinantibioticresistance(invasiveinfections),2002-2008.Source:EuropeanAntimicrobialResistanceSurveillanceSystem(EARSS),2009.20022007Me
4、thicillin-resistantStaphylococcusaureus(MRSA),bloodandspinalfluidNodata<1%1-5%5-10%10-25%25-50%>50%Source:EuropeanAntimicrobialResistanceSurveillanceSystem(EARSS),2008.5Methicillin-resistantStaphylococcusaureus(MRSA),EU,2007:oftenhigh,butdecreasinginmanycountriesCountrywi
5、thasignificantincrease(2005–2007)Countrywithasignificantdecrease(2005–2007)MRSA(%)Source:EARSS&ECDC,2009No.ofcountries6Antimicrobialresistanceingram-negativebacteria,EU,2007:alreadyhighorincreasingCountrywithasignificantincrease(2005-2007)Countrywithasignificantdecrease(
6、2005-2007)Carbapenem-resistantPseudomonasaeruginosa(%)3rd-gen.ceph.-resistantKlebsiellapneumoniae(%)3rd-gen.ceph.-resistantEscherichiacoli(%)Source:EARSS&ECDC,2009No.ofcountriesNo.ofcountries7Source:EuropeanSurveillanceofAntimicrobialConsumption(ESAC),2010.In:ECDCAnnualEpi
7、demiologicalReport2010:inpress.TotaloutpatientantibioticuseinEUMemberStates,IcelandandNorway,20088*Totaluse,i.e.includinginpatients(CY,GR,LT).**Reimbursementdata,i.e.notincludingover-the-countersaleswithoutaprescription(ES)***Datafrom2007(MT)Antibioticresistance–Apatients
8、afetyissueforallhospitalsTheemergence,selectionandspreadofresistantbacteriainhospitalsisa