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1、胰腺实性假乳头状瘤FudanCancerCenter陈其文Solid-PseudopapillaryTumorofPancreas(SPTP)Introduction1.Franzdescribedthistumorin1959asa“papillarytumorofthepancreas,benignormalignant”2.1996,WHOinitsclassificationofexocrinepancreatictumors,recognizedthemas“solidpseudopapillarytumors”ofthepancreas.3.Lowpotentiallymali
2、gnant,about10%havemalignantbehavior4.CapsuleintactornothasarelationtothemalignantbehaviorandrecurrenceaftersurgeryFranzVK.Tumorsofthepancreas.In:Atlasoftumorpathology:fasc27–28,ser7.Washington,DC:ArmedForcesInstituteofPathology,1959:32–33PapavramidisT,PapavramidisS.Solidpseudopapillarytumorsofthep
3、ancreas:reviewof718patientsreportedinEnglishliterature.JAmCollSurg,2005,200(6):965-9721.Unusualprimarytumorofthepancreasaccountfor9%ofthecystictumorofpancreasand1%-2.25%oftheexocrinepancreatictumors2.Withalowpotentialformalignancy3.Unknowncellorigin4.Seenmostlyinyoungwomen,maybeacceleratedbypregna
4、ncythemaletofemaleratiois1:9.5.KlimstraDS,WenigBM,HeffessCS.Solidpseudopapillarytumorofthepancreas:atypicallycysticcarcinomaoflowmalignantpotential.SeminDiagnPathol2000;17:66–80FeaturesAgedistributionofthepatientswithSPTPDistributionofPatientsAccordingtoTumorDiameterTUMORSITESPancreaticHead:39.8%T
5、ail:24.1%BodyandTail:19.5%Body:11.2%Neck:3.6%ExtrapancreaticSPTwasfoundin1.8%patientsMetastasisandInvasionMetastasis:Livermetastasisisseeninafewcases,andrarecasesoflymphnodemetastasis,peritonealspread,andmultiplicityhavebeenreportedExtracapsularInvasion:SPTPinfrequentlyinvadesacapsuleandthesurroun
6、dingstructures,mainlythespleen,portalvein,andduodenum.Of553patients,45(8.1%)werediagnosedasmalignantSPTPInvolvedOrgans:PortalVein/SpleenicVein/SuperiorMesentericVein:11OmentumorPeritoneum:7Duodenum:7Liver:6Spleen:4Stomach:3Colon:2DiaphragmaticMuscle:1LeftKidney:1PengFY,ZhenHH,XinBW,etal.Solidpseud
7、opapillarytumorodthepancreas:Areviewof553casesinChineseliterature.WorldJournalofGastroenterology.2010,16(10):1209-1214.TypicalandAtypicalSPTPTypicalSPTP:characterizedbyawell-encapsulatedmasswithvaryingamountsofin
