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1、EPIDEMIOLOGYandoverviewofcardiacDISEASEINTRODUCTIONThe20thcenturysawunparalleledincreaseinlifeexpectancy&majorshiftinthecauseofillnessthroughouttheworldGLOBALBURDENOFCVD.Acenturyago,CVDdeath<10%Today,approximately30%ofdeathsworldwideincludingnearly40%inhighincomecountriesandabout2
2、8%inlowandmiddleincomecountries-Braunwald’sHeartDisease2008EPIDEMIOLOGICALTRANSITIONSStageTypicalproportionofdeathscausedbyCVD%PredominanttypesofCVDPestilenceandFamine<10Rheumaticheartdisease,cardiomyopathiesRecedingPandemics10-35Rheumaticvalvulardisease,HT,CHD,StrokeContd…Degener
3、ative&Manmadediseases35–65CHD,StrokeDelayeddegenerativeDiseases40–50CHD,Stroke,CHF.PREVALENCEOFCHD-USAgeinyearsMale%Female%40-49070550-59130860-69161170-792214PREVALENCETheprevalenceofCHDisabout7.4%inmenand4.5%inwomen.Theprevalenceishigherinlowersocio-economicgroups.Ofnote,mortali
4、tyfromCHDisfallingbutmorbidityappearstoberising.EPIDEMIOLOGYOFIHDMORTALITYRATES-UKCHDisthemostcommoncauseofdeath(andprematuredeath)intheUK1in5menand1in6womendiefromCHDContd…Thereare101,000deathsfromCHDintheUKeachyear.DeathratesfromCHDhavefallenby46%forpeopleunder65yearsinthelast10
5、yearsinUK,Australia(48%)andNorway(54%).DeathfromCHDismorelikelyduringwinter.MORBIDITYRATESINUKTheaverageincidenceofMyocardialInfarctionis600per100,000inmenaged30-69and200per100,000inwomen.TheincidenceincreaseswithageThereareabout52,000newcasesofAnginaperyearinallmenlivingintheUKan
6、dabout43,000newcasesinwomenPREVALENCEOFCVD-UKDiseaseAge%HeartattackMenWomen04%02%AnginaMen55-64yrsWomen08%05%Men65-74yrsWomen17%08%NEWSALERTAug13,2009TheheartofthematterPrematureheartattackiscommoninIndianscomparedtotheWesternpopulationBeyondtheageof50,theriskofheartattackperyeara
7、pproximately2-3per1000Contd…Aug13,2009.TheHinduonein200deathsofadultsoverage40occursduetoSuddenCardiacArrestContd…November4,2006TheHinduMYSORE:IncidenceofheartdiseasehasdoubledinIndiaduringthelast20yearsonaccountofchangesinlifestyleandeconomicdevelopment.Contd…DrRajeshPande(Cardio
8、vasculardiseaseinIndiaandtheimpac